Evidence map›Paper›PMID 33672886›Full record

ArticleMicroorganisms2021

Ribonuclease J-Mediated mRNA Turnover Modulates Cell Shape, Metabolism and Virulence in

Truc Thanh Luong, Minh Tan Nguyen, Yi-Wei Chen, Chungyu Chang, Ju Huck Lee, Manuel Wittchen, HyLam Ton-That, Melissa Cruz, Danielle A Garsin, Asis Das and 2 more

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Inactivation of thebioRxiv : the preprint server for biology · 2025
    Article
  3. Article
  4. Article
  5. A cryptic oxidoreductase safeguards oxidative protein folding inProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  6. Frontiers in microbiology · 2023
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 4 countries.

Truc Thanh LuongDivision of Oral Biology & Medicine, School of Dentistry, University of California, Los Angeles, CA 90095, USA.
Minh Tan NguyenDivision of Oral Biology & Medicine, School of Dentistry, University of California, Los Angeles, CA 90095, USA.
Yi-Wei ChenDivision of Oral Biology & Medicine, School of Dentistry, University of California, Los Angeles, CA 90095, USA.
Chungyu ChangDivision of Oral Biology & Medicine, School of Dentistry, University of California, Los Angeles, CA 90095, USA.
Ju Huck LeeDepartment of Microbiology & Molecular Genetics, University of Texas Health Science Center, Houston, TX 77030, USA.
Manuel WittchenCenter for Biotechnology (CeBiTec), Bielefeld University, 33615 Bielefeld, Germany.
HyLam Ton-ThatDepartment of Chemistry, University of California at Irvine, Irvine, CA 92617, USA.
Melissa CruzDepartment of Microbiology & Molecular Genetics, University of Texas Health Science Center, Houston, TX 77030, USA.
Danielle A GarsinDepartment of Microbiology & Molecular Genetics, University of Texas Health Science Center, Houston, TX 77030, USA.ORCID 0000-0002-6551-2600
Asis DasNeag Comprehensive Cancer Center, Department of Medicine, University of Connecticut Health Center, Farmington, CT 06030, USA.
Andreas TauchCenter for Biotechnology (CeBiTec), Bielefeld University, 33615 Bielefeld, Germany.
Hung Ton-ThatDivision of Oral Biology & Medicine, School of Dentistry, University of California, Los Angeles, CA 90095, USA.ORCID 0000-0003-1611-0469
University of California, Los Angeles · USBielefeld University · DEKorea Research Institute of Bioscience and Biotechnology · KRThe University of Texas Health Science Center at Houston · USUConn Health · US

Funding

Molecular Assembly on the Cell Surface of ActinomycesR01DE017382 · NIDCR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI Hung Ton-That · 2008 to 2026
$6.7M
Post-translocational protein folding in Gram-positive bacteriaR01DE025015 · NIDCR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI TON-THAT, HUNG · 2015 to 2024
$3.9M
The Role of Reactive Oxygen Species in Mucosal Innate ImmunityR01AI076406 · NIAID · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI GARSIN, DANIELLE A · 2009 to 2019
$3.2M
Response To Immune Associated StressR01AI150045 · NIAID · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI GARSIN, DANIELLE A · 2020 to 2024
$2.6M
Post-initiation regulatory mechanisms controlling ethanolamine utilizationR01AI110432 · NIAID · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI GARSIN, DANIELLE A, WINKLER, WADE · 2015 to 2019
$2.2M
Post-initiation regulatory mechanisms controlling ethanolamine utilizationR56AI110432 · NIAID · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI GARSIN, DANIELLE A, WINKLER, WADE · 2014 to 2014
$431k
Division of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases AI076406 and AI150045NIAID NIH HHS R01 AI076406NIAID NIH HHS R01 AI110432NIAID NIH HHS R01 AI150045NIAID NIH HHS R56 AI110432NIDCR NIH HHS DE025015NIDCR NIH HHS R01 DE017382NIDCR NIH HHS R01 DE025015
6 · The paper itself

Abstract

Controlled RNA degradation is a crucial process in bacterial cell biology for maintaining proper transcriptome homeostasis and adaptation to changing environments. mRNA turnover in many Gram-positive bacteria involves a specialized ribonuclease called RNase J (RnJ). To date, however, nothing is known about this process in the diphtheria-causative pathogen

Indexed as

actinobacteriumCaenorhabditis elegansCorynebacterium diphtheriaemetabolismribonucleaseRNase Jsiderophoretryptophan biosynthesisvirulence

Identifiers

PMID33672886
PMCPMC7917786
OpenAlexW3130414237

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.