Evidence map›Paper›PMID 33672811›Full record

ArticleJournal of personalized medicine2021

ETS-Domain Transcription Factor Elk-1 Regulates Stemness Genes in Brain Tumors and CD133+ BrainTumor-Initiating Cells.

Melis Savasan Sogut, Chitra Venugopal, Basak Kandemir, Ugur Dag, Sujeivan Mahendram, Sheila Singh, Gizem Gulfidan, Kazim Yalcin Arga, Bayram Yilmaz, Isil Aksan Kurnaz

Open access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. ELK1 regulates BMPR1B transcriptional activity in ovine granulosa cells.Frontiers in cell and developmental biology · 2025
    Article
  2. Article
  3. BRCA1 and ELK-1 regulate neural progenitor cell fate in the optic tectum in response to visual experience inProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Melis Savasan SogutInstitute of Biotechnology, Gebze Technical University, 41400 Kocaeli, Turkey.
Chitra VenugopalStem Cell and Cancer Research Institute, McMaster University, Hamilton, ON L8S 4K1, Canada.
Basak KandemirInstitute of Biotechnology, Gebze Technical University, 41400 Kocaeli, Turkey.
Ugur DagBiotechnology Graduate Program, Graduate School of Sciences, Yeditepe University, 26 Agustos Yerlesimi, Kayisdagi, 34755 Istanbul, Turkey.
Sujeivan MahendramStem Cell and Cancer Research Institute, McMaster University, Hamilton, ON L8S 4K1, Canada.
Sheila SinghStem Cell and Cancer Research Institute, McMaster University, Hamilton, ON L8S 4K1, Canada.
Gizem GulfidanDepartment of Bioengineering, Marmara University, 34722 Istanbul, Turkey.ORCID 0000-0003-4150-0012
Kazim Yalcin ArgaDepartment of Bioengineering, Marmara University, 34722 Istanbul, Turkey.ORCID 0000-0002-6036-1348
Bayram YilmazDepartment of Physiology, Faculty of Medicine, Yeditepe University, 26 Agustos Yerlesimi, Kayisdagi, 34755 Istanbul, Turkey.
Isil Aksan KurnazInstitute of Biotechnology, Gebze Technical University, 41400 Kocaeli, Turkey.ORCID 0000-0002-5587-4763
Yeditepe University · TRMcMaster University · CAMarmara University · TRGebze Technical University · TR

Funding

TUBITAK 115Z804TUBITAK 211T167
6 · The paper itself

Abstract

Elk-1, a member of the ternary complex factors (TCFs) within the ETS (E26 transformation-specific) domain superfamily, is a transcription factor implicated in neuroprotection, neurodegeneration, and brain tumor proliferation. Except for known targets,

Indexed as

brain-tumor-initiating cell (BTIC)Elk-1ETSmicroarraystem cell

Identifiers

PMID33672811
PMCPMC7917801
OpenAlexW3133152986

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.