Evidence map›Paper›PMID 33672778›Full record

ReviewDiagnostics (Basel, Switzerland)2021

Cardiac Adiposity and Arrhythmias: The Role of Imaging.

Maria Bonou, Sophie Mavrogeni, Chris J Kapelios, George Markousis-Mavrogenis, Constantina Aggeli, Evangelos Cholongitas, Athanase D Protogerou, John Barbetseas

Open access · goldAbstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Cardiac Adipose Tissue Segmentation via Image-Level Annotations.IEEE journal of biomedical and health informatics · 2023
    Article
  4. Strain Imaging and Ventricular Arrhythmia.Diagnostics (Basel, Switzerland) · 2023
    Review
  5. Article
  6. Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Maria BonouDepartment of Cardiology, Laiko General Hospital, 11527 Athens, Greece.
Sophie MavrogeniDepartment of Cardiology, Onassis Cardiac Surgery Center, 17674 Athens, Greece.
Chris J KapeliosDepartment of Cardiology, Laiko General Hospital, 11527 Athens, Greece.ORCID 0000-0003-1616-6307
George Markousis-MavrogenisDepartment of Cardiology, Onassis Cardiac Surgery Center, 17674 Athens, Greece.ORCID 0000-0001-8192-6670
Constantina AggeliFirst Department of Cardiology, Hippokration General Hospital, Medical School of National & Kapodistrian University, 11527 Athens, Greece.
Evangelos CholongitasFirst Department of Internal Medicine, Medical School of National & Kapodistrian University, 11527 Athens, Greece.
Athanase D ProtogerouCardiovascular Prevention & Research Unit, Clinic and Laboratory of Pathophysiology, National & Kapodistrian University Athens School of Medicine, 11527 Athens, Greece.
John BarbetseasDepartment of Cardiology, Laiko General Hospital, 11527 Athens, Greece.
Laiko General Hospital of Athens · GRNational and Kapodistrian University of Athens · GROnassis Cardiac Surgery Center · GRHippocration General Hospital · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Increased cardiac fat depots are metabolically active tissues that have a pronounced pro-inflammatory nature. Increasing evidence supports a potential role of cardiac adiposity as a determinant of the substrate of atrial fibrillation and ventricular arrhythmias. The underlying mechanism appears to be multifactorial with local inflammation, fibrosis, adipocyte infiltration, electrical remodeling, autonomic nervous system modulation, oxidative stress and gene expression playing interrelating roles. Current imaging modalities, such as echocardiography, computed tomography and cardiac magnetic resonance, have provided valuable insight into the relationship between cardiac adiposity and arrhythmogenesis, in order to better understand the pathophysiology and improve risk prediction of the patients, over the presence of obesity and traditional risk factors. However, at present, given the insufficient data for the additive value of imaging biomarkers on commonly used risk algorithms, the use of different screening modalities currently is indicated for personalized risk stratification and prognostication in this setting.

Indexed as

adipose tissuearrhythmogenesisatrial fibrillationcardiac fatcardiac magnetic resonanceechocardiography

Identifiers

PMID33672778
PMCPMC7924558
OpenAlexW3132750150

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.