Evidence map›Paper›PMID 33672774›Full record

ReviewMolecules (Basel, Switzerland)2021

Microorganisms: A Potential Source of Bioactive Molecules for Antioxidant Applications.

Alka Rani, Khem Chand Saini, Felix Bast, Sanjeet Mehariya, Shashi Kant Bhatia, Roberto Lavecchia, Antonio Zuorro

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 148 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Glucan exopolysaccharide fromFrontiers in molecular biosciences · 2026
    Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. A NovelAntioxidants (Basel, Switzerland) · 2025
    Article
  16. Review
  17. Article
  18. Review
  19. Review
  20. Review

6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Alka RaniDepartment of Botany, School of Basic and Applied Sciences, Central University of Punjab, Bathinda, Punjab 151401, India.ORCID 0000-0001-8181-111X
Khem Chand SainiDepartment of Botany, School of Basic and Applied Sciences, Central University of Punjab, Bathinda, Punjab 151401, India.ORCID 0000-0001-5768-6507
Felix BastDepartment of Botany, School of Basic and Applied Sciences, Central University of Punjab, Bathinda, Punjab 151401, India.
Sanjeet MehariyaDepartment of Chemical Engineering, Materials and Environment, Sapienza University of Rome, 00184 Rome, Italy.ORCID 0000-0003-1801-4702
Shashi Kant BhatiaDepartment of Biological Engineering, College of Engineering, Konkuk University, Seoul 05029, Korea.ORCID 0000-0002-7688-6069
Roberto LavecchiaDepartment of Chemical Engineering, Materials and Environment, Sapienza University of Rome, 00184 Rome, Italy.
Antonio ZuorroDepartment of Chemical Engineering, Materials and Environment, Sapienza University of Rome, 00184 Rome, Italy.ORCID 0000-0002-8173-3809
Central University of Punjab · INSapienza University of Rome · ITKonkuk University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxidative stress originates from an elevated intracellular level of free oxygen radicals that cause lipid peroxidation, protein denaturation, DNA hydroxylation, and apoptosis, ultimately impairing cell viability. Antioxidants scavenge free radicals and reduce oxidative stress, which further helps to prevent cellular damage. Medicinal plants, fruits, and spices are the primary sources of antioxidants from time immemorial. In contrast to plants, microorganisms can be used as a source of antioxidants with the advantage of fast growth under controlled conditions. Further, microbe-based antioxidants are nontoxic, noncarcinogenic, and biodegradable as compared to synthetic antioxidants. The present review aims to summarize the current state of the research on the antioxidant activity of microorganisms including actinomycetes, bacteria, fungi, protozoa, microalgae, and yeast, which produce a variety of antioxidant compounds, i.e., carotenoids, polyphenols, vitamins, and sterol, etc. Special emphasis is given to the mechanisms and signaling pathways followed by antioxidants to scavenge Reactive Oxygen Species (ROS), especially for those antioxidant compounds that have been scarcely investigated so far.

Indexed as

AntioxidantsBacteriaFungiMicroalgaeMolecular StructureAntioxidantsastaxanthinmicroalgaemycothiolnatural antioxidantoxidative stressperoxiredoxin

Identifiers

PMID33672774
PMCPMC7924645
OpenAlexW3130059566

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.