Evidence map›Paper›PMID 33672685›Full record

ReviewAntibiotics (Basel, Switzerland)2021

Attacins: A Promising Class of Insect Antimicrobial Peptides.

Francesco Buonocore, Anna Maria Fausto, Giulia Della Pelle, Tomislav Roncevic, Marco Gerdol, Simona Picchietti

Open access · goldAbstract readReview
In one paragraph

Review in Antibiotics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
8.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 87 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Mechanism, Efficacy, and Safety of Natural Antibiotics.Antibiotics (Basel, Switzerland) · 2025
    Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Impact ofInsects · 2025
    Article
  12. Article
  13. Cell-death induced immune response and coagulopathy promote cachexia inbioRxiv : the preprint server for biology · 2025
    Article
  14. Review
  15. Review
  16. The Black Soldier FlyCurrent research in microbial sciences · 2025
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Francesco BuonocoreDepartment for Innovation in Biological, Agro-food and Forest systems, University of Tuscia, Largo dell'Università snc, 05100 Viterbo, VT, Italy.ORCID 0000-0001-8045-5651
Anna Maria FaustoDepartment for Innovation in Biological, Agro-food and Forest systems, University of Tuscia, Largo dell'Università snc, 05100 Viterbo, VT, Italy.
Giulia Della PelleDepartment for Innovation in Biological, Agro-food and Forest systems, University of Tuscia, Largo dell'Università snc, 05100 Viterbo, VT, Italy.ORCID 0000-0002-8110-1932
Tomislav RoncevicDepartment of Biology, Faculty of Science, University of Split, Rudera Boskovica 33, 21000 Split, Croatia.ORCID 0000-0002-6426-6655
Marco GerdolDepartment of Life Sciences, University of Trieste, Via Giorgieri 5, 34127 Trieste, TS, Italy.ORCID 0000-0001-6411-0813
Simona PicchiettiDepartment for Innovation in Biological, Agro-food and Forest systems, University of Tuscia, Largo dell'Università snc, 05100 Viterbo, VT, Italy.ORCID 0000-0002-6116-213X
Università degli Studi della Tuscia · ITUniversity of Split · HRUniversity of Trieste · IT

Funding

Ministero dell'Istruzione, dell'Università e della Ricerca Department of Excellence-2018
6 · The paper itself

Abstract

Insects produce a large repertoire of antimicrobial peptides (AMPs) as the first line of defense against bacteria, viruses, fungi or parasites. These peptides are produced from a large precursor that contains a signal domain, which is cleaved in vivo to produce the mature protein with antimicrobial activity. At present, AMPs from insects include several families which can be classified as cecropins, ponericins, defensins, lebocins, drosocin, Metchnikowin, gloverins, diptericins and attacins according to their structure and/or function. This short review is focused on attacins, a class of glycine-rich peptides/proteins that have been first discovered in the cecropia moth (

Indexed as

antimicrobial activityattacinsinsect AMPspharmacological applications

Identifiers

PMID33672685
PMCPMC7924397
OpenAlexW3129310864

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.