Evidence map›Paper›PMID 33672634›Full record

ReviewInternational journal of molecular sciences2021

The Endocannabinoid System and Invertebrate Neurodevelopment and Regeneration.

Tristyn L Clarke, Rachael L Johnson, Jonathan J Simone, Robert L Carlone

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 24 citations in OpenAlex.

  1. The endocannabinoid system regulates both ependymoglial and neuronal cell responses to a tail amputation in the axolotl.Developmental dynamics : an official publication of the American Association of Anatomists · 2026
    Article
  2. The paraEuropean journal of pain (London, England) · 2026
    Article
  3. Article
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  8. Review
  9. Pan-phylumFrontiers in endocrinology · 2022
    Article
  10. In Vivo Evaluation ofPharmaceuticals (Basel, Switzerland) · 2021
    Article
  11. The Endocannabinoid System in the Mediterranean MusselInternational journal of molecular sciences · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Tristyn L ClarkeDepartment of Biological Sciences, Brock University, 1812 Sir Isaac brock Way, St. Catharines, ON L2S 3A1, Canada.
Rachael L JohnsonDepartment of Biological Sciences, Brock University, 1812 Sir Isaac brock Way, St. Catharines, ON L2S 3A1, Canada.ORCID 0000-0002-6280-4819
Jonathan J SimoneDepartment of Biological Sciences, Brock University, 1812 Sir Isaac brock Way, St. Catharines, ON L2S 3A1, Canada.
Robert L CarloneDepartment of Biological Sciences, Brock University, 1812 Sir Isaac brock Way, St. Catharines, ON L2S 3A1, Canada.ORCID 0000-0002-5007-2921
Brock University · CA

Funding

Natural Sciences and Engineering Research Council of Canada RGPIN-2019-06380
6 · The paper itself

Abstract

Cannabis has long been used for its medicinal and psychoactive properties. With the relatively new adoption of formal medicinal cannabis regulations worldwide, the study of cannabinoids, both endogenous and exogenous, has similarly flourished in more recent decades. In particular, research investigating the role of cannabinoids in regeneration and neurodevelopment has yielded promising results in vertebrate models. However, regeneration-competent vertebrates are few, whereas a myriad of invertebrate species have been established as superb models for regeneration. As such, this review aims to provide a comprehensive summary of the endocannabinoid system, with a focus on current advances in the area of endocannabinoid system contributions to invertebrate neurodevelopment and regeneration.

Indexed as

RegenerationAnimalsEndocannabinoidsHumansInvertebratesModels, BiologicalNervous SystemSynapsesEndocannabinoids2-AGAEACB1CB2endocannabinoidinvertebrateneurodevelopmentregeneration

Identifiers

PMID33672634
PMCPMC7924210
OpenAlexW3130287016

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.