Evidence map›Paper›PMID 33672607›Full record

ReviewCancers2021

Unmet Medical Needs and Future Perspectives for Leiomyosarcoma Patients-A Position Paper from the National LeioMyoSarcoma Foundation (NLMSF) and Sarcoma Patients EuroNet (SPAEN).

Bernd Kasper, Annie Achee, Kathrin Schuster, Roger Wilson, Gerard van Oortmerssen, Rebecca A Gladdy, Matthew L Hemming, Paul Huang, Matthew Ingham, Robin L Jones and 9 more

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Radiomic-based prediction of lesion-specific systemic treatment response in metastatic disease.Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society · 2024
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. What Clinical Trials Are Needed for Treatment of Leiomyosarcoma?Current treatment options in oncology · 2022
    Review
  8. Review
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 14 institutions in 5 countries.

Bernd KasperMannheim University Medical Center, University of Heidelberg, 68167 Mannheim, Germany.ORCID 0000-0001-8425-8356
Annie AcheeNational LeioMyoSarcoma Foundation (NLMSF), Denver, CO 80222, USA.
Kathrin SchusterSarcoma Patients EuroNet, SPAEN, 61200 Wölfersheim, Germany.
Roger WilsonSarcoma Patients EuroNet, SPAEN, 61200 Wölfersheim, Germany.
Gerard van OortmerssenSarcoma Patients EuroNet, SPAEN, 61200 Wölfersheim, Germany.
Rebecca A GladdyDepartment of Surgery, Mount Sinai Hospital, Toronto, ON M5G 1XS, Canada.ORCID 0000-0003-4143-6620
Matthew L HemmingDana-Farber Cancer Institute, Boston, MA 02215, USA.ORCID 0000-0003-4674-7778
Paul HuangInstitute of Cancer Research, London SM2 5NG, UK.
Matthew InghamDepartment of Medicine, Columbia University School of Medicine, New York, NY 10032, USA.
Robin L JonesInstitute of Cancer Research, London SM2 5NG, UK.ORCID 0000-0003-4173-3844
Seth M PollackNorthwestern Medicine, Feinberg School of Medicine, Chicago, IL 60611, USA.
Denise ReinkeSarcoma Alliance for Research through Collaboration (SARC), Ann Arbor, MI 48105, USA.
Roberta SanfilippoFondazione IRCCS Istituto Nazionale dei Tumori, 20133 Milan, Italy.
Scott M SchuetzeMichigan Medicine Sarcoma Clinic, Rogel Cancer Center, Ann Arbor, MI 48109, USA.
Neeta SomaiahDepartment of Sarcoma Medical Oncology, The University of Texas MD Anderson Cancer Care Center, Houston, TX 77030, USA.
Brian A Van TineBarnes and Jewish Hospital, Washington University in St. Louis, St. Louis, MO 63110, USA.ORCID 0000-0003-4572-6668
Breelyn WilkyDepartment of Sarcoma Medical Oncology, Anschutz Medical Campus, University of Colorado, Aurora, CO 80045, USA.
Scott OkunoDivision of Medical Oncology, Mayo Clinic, Rochester, MN 55905, USA.
Jonathan TrentSylvester Comprehensive Cancer Center, University of Miami, Miami, FL 33136, USA.ORCID 0000-0001-6169-5238
Institute of Cancer Research · GBBarnes-Jewish Hospital · USColumbia University · USDana-Farber Cancer Institute · USFondazione IRCCS Istituto Nazionale dei Tumori · ITHeidelberg University · DEMayo Clinic in Arizona · USMichigan Medicine · USMount Sinai Hospital · CANorthwestern Medicine · USSarcoma Alliance for Research through Collaboration · USThe University of Texas MD Anderson Cancer Center · USUniversity of Colorado Anschutz Medical Campus · USUniversity of Miami · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As leiomyosarcoma patients are challenged by the development of metastatic disease, effective systemic therapies are the cornerstone of outcome. However, the overall activity of the currently available conventional systemic treatments and the prognosis of patients with advanced or metastatic disease are still poor, making the treatment of this patient group challenging. Therefore, in a joint effort together with patient networks and organizations, namely Sarcoma Patients EuroNet (SPAEN), the international network of sarcoma patients organizations, and the National LeioMyoSarcoma Foundation (NLMSF) in the United States, we aim to summarize state-of-the-art treatments for leiomyosarcoma patients in order to identify knowledge gaps and current unmet needs, thereby guiding the community to design innovative clinical trials and basic research and close these research gaps. This position paper arose from a leiomyosarcoma research meeting in October 2020 hosted by the NLMSF and SPAEN.

Indexed as

leiomyosarcomaNLMSFresearchSPAENtreatment

Identifiers

PMID33672607
PMCPMC7924026
OpenAlexW3132243751

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.