Evidence map›Paper›PMID 33672578›Full record

ReviewAntioxidants (Basel, Switzerland)2021

Recent Progress in Discovering the Role of Carotenoids and Metabolites in Prostatic Physiology and Pathology-A Review-Part II: Carotenoids in the Human Studies.

Joanna Dulińska-Litewka, Przemysław Hałubiec, Agnieszka Łazarczyk, Oskar Szafrański, Yoav Sharoni, James A McCubrey, Bartosz Gąsiorkiewicz, Torsten Bohn

Open access · goldAbstract readReview
In one paragraph

Review in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 4 countries.

Joanna Dulińska-LitewkaChair of Medical Biochemistry Medical College, Jagiellonian University, 31-034 Cracow, Poland.ORCID 0000-0002-6376-496X
Przemysław HałubiecChair of Medical Biochemistry Medical College, Jagiellonian University, 31-034 Cracow, Poland.ORCID 0000-0002-7759-6039
Agnieszka ŁazarczykChair of Medical Biochemistry Medical College, Jagiellonian University, 31-034 Cracow, Poland.
Oskar SzafrańskiChair of Medical Biochemistry Medical College, Jagiellonian University, 31-034 Cracow, Poland.
Yoav SharoniDepartment of Clinical Biochemistry, Faculty of Health Sciences, Ben-Gurion University of the Negev, P.O. Box 653 Beer Sheva, Israel.ORCID 0000-0002-1898-1666
James A McCubreyDepartment of Microbiology and Immunology, Brody Medical Sciences Building, East Carolina University, Greenville, NC 27834, USA.ORCID 0000-0001-6027-3156
Bartosz GąsiorkiewiczChair of Medical Biochemistry Medical College, Jagiellonian University, 31-034 Cracow, Poland.
Torsten BohnNutrition and Health Research Group 1 A-B, Population Health Department, Luxembourg Institute of Health, rue Thomas Edison, L-23 1445 Strassen, Luxembourg.ORCID 0000-0002-7825-0697
Jagiellonian University · PLBen-Gurion University of the Negev · ILEast Carolina University · USLuxembourg Institute of Health · LU

Funding

European Cooperation in Science and Technology (COST) Action , European Network to Advance Carotenoid Research and Applications in Agro-Food and Health CA15136MNSiW N41/DBS/000431
6 · The paper itself

Abstract

Among the vast variety of plant-derived phytochemicals, the group of carotenoids has continuously been investigated in order to optimize their potential application in the area of dietary intervention related to chronic diseases. One organ that has been especially targeted in many of these studies and clinical trials is the human prostate. Without doubt, carotenoids (and their endogenous derivatives-retinoids and apo-carotenoids) are involved in a plethora of intra- and intercellular signaling, cell growth, and differentiation of prostate tissue. Due to the accumulation of new data on the role of different carotenoids, such as lycopene (LYC) and β-carotene (BC), in prostatic physiology and pathology, the present review aimed to cover the past ten years of research in this regard. Data from experimental studies are presented in the first part of the review, while epidemiological studies are disclosed in this second part. The objective of this compilation was to emphasize the present state of knowledge about the most potent molecular targets of carotenoids, as well as to propose promising carotenoid agents for the prevention and possible treatment of prostatic diseases.

Indexed as

antioxidants, cohort studiesapo-carotenoidsbeta-carotenelycopenemetabolismprostate cancervitamin A

Identifiers

PMID33672578
PMCPMC7924028
OpenAlexW3133222056

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.