Evidence map›Paper›PMID 33672575›Full record

ArticleGeriatrics (Basel, Switzerland)2021

Potentially Inappropriate Medication Use and Hard Braking Events in Older Drivers.

Yuqing Xue, Stanford Chihuri, Howard F Andrews, Marian E Betz, Carolyn DiGuiseppi, David W Eby, Linda L Hill, Vanya Jones, Thelma J Mielenz, Lisa J Molnar and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Geriatrics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Yuqing XueDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY 10032, USA.
Stanford ChihuriDepartment of Anesthesiology, Vagelos College of Physicians and Surgeons, Columbia University,New York, NY 10032, USA.
Howard F AndrewsDepartment of Psychiatry, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA.
Marian E BetzDepartment of Emergency Medicine, University of Colorado School of Medicine, Aurora, CO 80045, USA.
Carolyn DiGuiseppiDepartment of Epidemiology, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.ORCID 0000-0002-6440-7817
David W EbyUniversity of Michigan Transportation Research Institute, Ann Arbor, MI 48109, USA.ORCID 0000-0001-8650-0628
Linda L HillSchool of Public Health, University of California San Diego, La Jolla, CA 92093, USA.
Vanya JonesDepartment of Health, Behavior and Society, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.
Thelma J MielenzDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY 10032, USA.
Lisa J MolnarUniversity of Michigan Transportation Research Institute, Ann Arbor, MI 48109, USA.
David StrogatzBassett Research Institute, Cooperstown, NY 13326, USA.ORCID 0000-0002-5805-6280
Barbara H LangDepartment of Anesthesiology, Vagelos College of Physicians and Surgeons, Columbia University,New York, NY 10032, USA.
Tara Kelley-BakerAAA Foundation for Traffic Safety, Washington, DC 20005, USA.
Guohua LiDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY 10032, USA.ORCID 0000-0003-4732-2448

Funding

AAA Foundation for Traffic Safety Contract No. 51178B
6 · The paper itself

Abstract

Potentially inappropriate medications (PIMs) identified by the American Geriatrics Society should generally be avoided by older adults because of ineffectiveness or excess risk of adverse effects. Few studies have examined the effects of PIMs on driving safety measured by prospectively and objectively collected driving data. Data for this study came from the Longitudinal Research on Aging Drivers study, a multisite naturalistic driving study of older adults. Multivariable negative binominal modeling was used to estimate incidence rate ratios and 95% confidence intervals of hard braking events (proxies for unsafe driving behavior defined as events with a deceleration rate ≥0.4 g) associated with PIM use among older drivers. The study sample consisted of 2932 drivers aged 65-79 years at baseline, including 542 (18.5%) who used at least one PIM. These drivers were followed through an in-vehicle recording device for up to 44 months. The overall incidence of hard braking events was 1.16 per 1000 miles. Use of PIMs was associated with a 10% increased risk of hard braking events. Compared to drivers who were not using PIMs, the risk of hard braking events increased 6% for those using one PIM, and 24% for those using two or more PIMs. Use of PIMs by older adult drivers is associated in a dose-response fashion with elevated risks of hard braking events. Reducing PIM use in older adults might help improve driving safety as well as health outcomes.

Indexed as

agingdriving safetyhard braking eventspotentially inappropriate medications

Identifiers

PMID33672575
PMCPMC8005989

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.