Evidence map›Paper›PMID 33672564›Full record

ArticleVaccines2021

Antibody Response to Canine Parvovirus Vaccination in Dogs with Hypothyroidism Treated with Levothyroxine.

Michèle Bergmann, Monika Freisl, Katrin Hartmann, Stephanie Speck, Uwe Truyen, Yury Zablotski, Matthias Mayr, Astrid Wehner

Open access · goldAbstract read
In one paragraph

Article in Vaccines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Michèle BergmannClinic of Small Animal Medicine, LMU Munich, Veterinaerstrasse 13, 80539 Munich, Germany.
Monika FreislClinic of Small Animal Medicine, LMU Munich, Veterinaerstrasse 13, 80539 Munich, Germany.
Katrin HartmannClinic of Small Animal Medicine, LMU Munich, Veterinaerstrasse 13, 80539 Munich, Germany.
Stephanie SpeckInstitute of Animal Hygiene and Veterinary Public Health, University of Leipzig, An den Tierkliniken 1, 04103 Leipzig, Germany.
Uwe TruyenInstitute of Animal Hygiene and Veterinary Public Health, University of Leipzig, An den Tierkliniken 1, 04103 Leipzig, Germany.
Yury ZablotskiClinic of Small Animal Medicine, LMU Munich, Veterinaerstrasse 13, 80539 Munich, Germany.
Matthias MayrClinic of Small Animal Medicine, LMU Munich, Veterinaerstrasse 13, 80539 Munich, Germany.
Astrid WehnerClinic of Small Animal Medicine, LMU Munich, Veterinaerstrasse 13, 80539 Munich, Germany.
Ludwig-Maximilians-Universität München · DELeipzig University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: No information is available on how dogs with hypothyroidism (HypoT) respond to vaccination. This study measured pre- and post-vaccination anti-canine parvovirus (CPV) antibodies in dogs with HypoT treated with levothyroxine and compared the results to those of healthy dogs. (2) Methods: Six dogs with HypoT and healthy age-matched control dogs (n = 23) were vaccinated against CPV with a modified-live vaccine. Hemagglutination inhibition was used to measure antibodies on days 0, 7, and 28. The comparison of the vaccination response of dogs with HypoT and healthy dogs were performed with univariate analysis. (3) Results: Pre-vaccination antibodies (≥10) were detected in 100% of dogs with HypoT (6/6; 95% CI: 55.7-100) and in 100% of healthy dogs (23/23; 95% CI: 83.1-100.0). A ≥4-fold titer increase was observed in none of the dogs with HypoT and in 4.3% of the healthy dogs (1/23; CI

Indexed as

CPVimmunosuppressionlevothyroxineMLVprotectionT4titer

Identifiers

PMID33672564
PMCPMC7924029
OpenAlexW3133224622

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.