Evidence map›Paper›PMID 33672521›Full record

ArticleInternational journal of environmental research and public health2021

Metabolic Syndromes as Important Comorbidities in Patients of Inherited Retinal Degenerations: Experiences from the Nationwide Health Database and a Large Hospital-Based Cohort.

Guann-Jye Chiou, Ding-Siang Huang, Fung-Rong Hu, Chung-May Yang, Chang-Hao Yang, Ching-Wen Huang, Jou-Wei Lin, Chao-Wen Lin, Tzyy-Chang Ho, Yi-Ting Hsieh and 5 more

Abstract read
In one paragraph

Article in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Guann-Jye ChiouDepartment of Medical Education, National Taiwan University Hospital, Taipei 100, Taiwan.ORCID 0000-0002-0282-8800
Ding-Siang HuangDepartment of Ophthalmology, National Taiwan University Hospital, Taipei 100, Taiwan.
Fung-Rong HuDepartment of Ophthalmology, National Taiwan University Hospital, Taipei 100, Taiwan.
Chung-May YangDepartment of Ophthalmology, National Taiwan University Hospital, Taipei 100, Taiwan.
Chang-Hao YangDepartment of Ophthalmology, National Taiwan University Hospital, Taipei 100, Taiwan.
Ching-Wen HuangDepartment of Ophthalmology, National Taiwan University Hospital, Taipei 100, Taiwan.
Jou-Wei LinCardiovascular Center, National Taiwan University Hospital (Yun-Lin Branch), Yunlin 632, Taiwan.
Chao-Wen LinDepartment of Ophthalmology, National Taiwan University Hospital, Taipei 100, Taiwan.
Tzyy-Chang HoDepartment of Ophthalmology, National Taiwan University Hospital, Taipei 100, Taiwan.
Yi-Ting HsiehDepartment of Ophthalmology, National Taiwan University Hospital, Taipei 100, Taiwan.ORCID 0000-0003-2258-154X
Tso-Ting LaiDepartment of Ophthalmology, National Taiwan University Hospital, Taipei 100, Taiwan.ORCID 0000-0002-8247-7018
Ho-Min ChenHealth Data Research Center, National Taiwan University, Taipei 100, Taiwan.
Pei-Lung ChenGraduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei 100, Taiwan.ORCID 0000-0002-5640-3074
Chuhsing Kate HsiaoInstitute of Epidemiology and Preventive Medicine, National Taiwan University, Taipei 100, Taiwan.
Ta-Ching ChenDepartment of Ophthalmology, National Taiwan University Hospital, Taipei 100, Taiwan.ORCID 0000-0003-4358-6585

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to evaluate the medical and socioeconomic impacts of IRDs using the nationwide health database and a large hospital-based cohort. This retrospective cross-sectional cohort study used data from the nationwide National Health Insurance Research Database (NHIRD). All patients with IRD from January 2012 to December 2016 were selected from the NHIRD and matched with the general population at a ratio of 1:4. All variables, including comorbidities, medications, service utilization, and medical costs, within 1 year from the date of the IRD diagnosis, were analyzed. Disability data were retrieved from the Taiwan Inherited retinal degeneration Project (TIP), a medical center-based database. A total of 4447 and 17,788 subjects from the nationwide database were included in the IRD and control groups, respectively. The Charlson comorbidity index score was higher in the IRD group (0.74:0.52,

Indexed as

Metabolic SyndromeRetinal DegenerationCohort StudiesComorbidityCross-Sectional StudiesHospitalsHumansRetrospective StudiesTaiwanCharlson comorbidity indexinherited retinal degenerationsmetabolic syndromesocioeconomic impacts

Identifiers

PMID33672521
PMCPMC7923804

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.