Evidence map›Paper›PMID 33672422›Full record

ArticleGenes2021

Differential Expression of

Lorissa I McDougall, Ryan M Powell, Magdalena Ratajska, Chi F Lynch-Sutherland, Sultana Mehbuba Hossain, George A R Wiggins, Agnieszka Harazin-Lechowska, Bożena Cybulska-Stopa, Jyoti Motwani, Erin C Macaulay and 4 more

Open access · goldAbstract read
In one paragraph

Article in Genes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. BARD1: A Friend or Foe in Pancreatic Ductal Adenocarcinoma?International journal of molecular sciences · 2025
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

Lorissa I McDougallDepartment of Pathology, Otago Medical School, Dunedin Campus, University of Otago, Dunedin 9010, New Zealand.
Ryan M PowellDepartment of Pathology, Otago Medical School, Dunedin Campus, University of Otago, Dunedin 9010, New Zealand.ORCID 0000-0002-6270-9758
Magdalena RatajskaDepartment of Pathology, Otago Medical School, Dunedin Campus, University of Otago, Dunedin 9010, New Zealand.ORCID 0000-0001-7015-1865
Chi F Lynch-SutherlandDepartment of Pathology, Otago Medical School, Dunedin Campus, University of Otago, Dunedin 9010, New Zealand.ORCID 0000-0002-0395-1878
Sultana Mehbuba HossainDepartment of Pathology, Otago Medical School, Dunedin Campus, University of Otago, Dunedin 9010, New Zealand.
George A R WigginsDepartment of Pathology and Biomedical Science, University of Otago, Christchurch 8011, New Zealand.
Agnieszka Harazin-LechowskaDepartment of Tumour Pathology, Maria Sklodowska-Curie National Research Institute of Oncology, Cracow Branch, 8011 Cracow, Poland.ORCID 0000-0002-3487-262X
Bożena Cybulska-StopaDepartment of Clinical Oncology, Maria Sklodowska-Curie National Research Institute of Oncology, Cracow Branch, 8011 Cracow, Poland.ORCID 0000-0002-0975-850X
Jyoti MotwaniDepartment of Pathology, Otago Medical School, Dunedin Campus, University of Otago, Dunedin 9010, New Zealand.
Erin C MacaulayDepartment of Pathology, Otago Medical School, Dunedin Campus, University of Otago, Dunedin 9010, New Zealand.
Glen ReidDepartment of Pathology, Otago Medical School, Dunedin Campus, University of Otago, Dunedin 9010, New Zealand.ORCID 0000-0001-6465-5223
Logan C WalkerDepartment of Pathology and Biomedical Science, University of Otago, Christchurch 8011, New Zealand.
Janusz RyśDepartment of Tumour Pathology, Maria Sklodowska-Curie National Research Institute of Oncology, Cracow Branch, 8011 Cracow, Poland.
Michael R EcclesDepartment of Pathology, Otago Medical School, Dunedin Campus, University of Otago, Dunedin 9010, New Zealand.ORCID 0000-0002-6824-8761
University of Otago · NZThe Maria Sklodowska-Curie National Research Institute of Oncology · PLGdańsk Medical University · PLMaurice Wilkins Centre · NZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Melanoma comprises <5% of cutaneous malignancies, yet it causes a significant proportion of skin cancer-related deaths worldwide. While new therapies for melanoma have been developed, not all patients respond well. Thus, further research is required to better predict patient outcomes. Using long-range nanopore sequencing, RT-qPCR, and RNA sequencing analyses, we examined the transcription of

Indexed as

Alternative SplicingCell Line, TumorGene Expression Regulation, NeoplasticHumansMelanomaNanopore SequencingProtein IsoformsRNA-SeqTumor Suppressor ProteinsUbiquitin-Protein LigasesBARD1 protein, humanProtein IsoformsTumor Suppressor ProteinsUbiquitin-Protein LigasesBARD1melanomananopore sequencingRNA-Seq

Identifiers

PMID33672422
PMCPMC7927127
OpenAlexW3129810982

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.