Evidence map›Paper›PMID 33672412›Full record

ArticleBrain sciences2021

Inhibition of the Sodium Calcium Exchanger Suppresses Alcohol Withdrawal-Induced Seizure Susceptibility.

Jamila Newton, Luli Rebecca Akinfiresoye, Prosper N'Gouemo

Open access · goldAbstract read
In one paragraph

Article in Brain sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Astrocyte-neuron circuits in epilepsy.Neurobiology of disease · 2023
    Review
  6. Article
  7. Frontiers in pharmacology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jamila NewtonDepartment of Physiology and Biophysics, Howard University College of Medicine, Washington, DC 20059, USA.
Luli Rebecca AkinfiresoyeDepartment of Physiology and Biophysics, Howard University College of Medicine, Washington, DC 20059, USA.
Prosper N'GouemoDepartment of Physiology and Biophysics, Howard University College of Medicine, Washington, DC 20059, USA.ORCID 0000-0002-7829-7292
Howard University · US

Funding

Na+/Ca2+ exchanger remodeling in alcohol withdrawal seizuresR01AA027660 · NIAAA · HOWARD UNIVERSITY · PI N'GOUEMO, PROSPER · 2019 to 2023
$1.7M
Pediatric seizures: role of IP3R Ca2+ release channelsR21AA027171 · NIAAA · HOWARD UNIVERSITY · PI N'GOUEMO, PROSPER · 2018 to 2019
$408k
NIAAA NIH HHS R01 AA027660NIAAA NIH HHS R21 AA027171
6 · The paper itself

Abstract

Calcium influx plays important roles in the pathophysiology of seizures, including acoustically evoked alcohol withdrawal-induced seizures (AWSs). One Ca

Indexed as

calcium signalinggeneralized tonic–clonic seizuresKB-R7943SN-6

Identifiers

PMID33672412
PMCPMC7926990
OpenAlexW3131047013

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.