Evidence map›Paper›PMID 33672380›Full record

ArticleMolecules (Basel, Switzerland)2021

Sunflower-Like Nanostructure with Built-In Hotspots for Alpha-Fetoprotein Detection.

Xiaoyu Zhao, Aonan Zhu, Yaxin Wang, Yongjun Zhang, Xiaolong Zhang

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Xiaoyu ZhaoSchool of Material and Environmental Engineering, Hangzhou Dianzi University, Hangzhou 310018, China.
Aonan ZhuCollege of Chemistry, Nankai University, Tianjin 300071, China.
Yaxin WangSchool of Material and Environmental Engineering, Hangzhou Dianzi University, Hangzhou 310018, China.
Yongjun ZhangSchool of Material and Environmental Engineering, Hangzhou Dianzi University, Hangzhou 310018, China.
Xiaolong ZhangCollege of Physics, Jilin Normal University, Changchun 130103, China.
Hangzhou Dianzi University · CNJilin Normal University · CNNankai University · CN

Funding

National Natural Science Foundation of China 51901060,61675090
6 · The paper itself

Abstract

In the present study, a sunflower-like nanostructure array composed of a series of synaptic nanoparticles and nanospheres was manufactured through an efficient and low-cost colloidal lithography technique. The primary electromagnetic field contribution generated by the synaptic nanoparticles of the surface array structures was also determined by a finite-difference time-domain software to simulate the hotspots. This structure exhibited high repeatability and excellent sensitivity; hence, it was used as a surface-enhanced Raman spectroscopy (SERS) active substrate to achieve a rapid detection of ultra-low concentrations of Alpha-fetoprotein (AFP). This study demonstrates the design of a plasmonic structure with strong electromagnetic coupling, which can be used for the rapid detection of AFP concentration in clinical medicine.

Indexed as

alpha-FetoproteinsColloidsElectromagnetic FieldsNanostructuresParticle SizeSoftwareSpectrum Analysis, RamanSurface Propertiesalpha-FetoproteinsColloidsalpha-fetoproteinLSPRSERS

Identifiers

PMID33672380
PMCPMC7926938
OpenAlexW3131783454

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.