Evidence map›Paper›PMID 33672373›Full record

ArticlePharmaceutics2021

The Use of a Non-Conventional Long-Lived Gallium Radioisotope

Maryam Oroujeni, Tianqi Xu, Katherine Gagnon, Sara S Rinne, Jan Weis, Javad Garousi, Ken G Andersson, John Löfblom, Anna Orlova, Vladimir Tolmachev

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Towards Radiolabeled EGFR-Specific Peptides: Alternatives to GE11.Pharmaceuticals (Basel, Switzerland) · 2023
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. PET and SPECT Imaging of the EGFR Family (RTK Class I) in Oncology.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Maryam OroujeniDepartment of Immunology, Genetics and Pathology, Uppsala University, 75185 Uppsala, Sweden.ORCID 0000-0003-2660-9837
Tianqi XuDepartment of Immunology, Genetics and Pathology, Uppsala University, 75185 Uppsala, Sweden.ORCID 0000-0002-1826-4093
Katherine GagnonGE Healthcare, GEMS PET Systems, 75015 Uppsala, Sweden.
Sara S RinneDepartment of Medicinal Chemistry, Uppsala University, 75183 Uppsala, Sweden.
Jan WeisDepartment of Medical Physics, Uppsala University Hospital, 75185 Uppsala, Sweden.ORCID 0000-0003-2448-9245
Javad GarousiDepartment of Immunology, Genetics and Pathology, Uppsala University, 75185 Uppsala, Sweden.ORCID 0000-0002-7224-6304
Ken G AnderssonDepartment of Protein Science, KTH Royal Institute of Technology, 10691 Stockholm, Sweden.
John LöfblomDepartment of Protein Science, KTH Royal Institute of Technology, 10691 Stockholm, Sweden.ORCID 0000-0001-9423-0541
Anna OrlovaDepartment of Medicinal Chemistry, Uppsala University, 75183 Uppsala, Sweden.ORCID 0000-0001-6120-2683
Vladimir TolmachevDepartment of Immunology, Genetics and Pathology, Uppsala University, 75185 Uppsala, Sweden.ORCID 0000-0002-6122-1734
Uppsala University · SEKTH Royal Institute of Technology · SEUppsala University Hospital · SE

Funding

Cancerfonden 20 1090Cancerfonden 2017/649Cancerfonden CAN 2018/436Cancerfonden CAN 2020/815Vetenskapsrådet 2019-00986Vetenskapsrådet 2019-00994Vetenskapsrådet 2019-05115VINNOVA 2019/00104
6 · The paper itself

Abstract

Epidermal growth factor receptor (EGFR) is overexpressed in many malignancies. EGFR-targeted therapy extends survival of patients with disseminated cancers. Radionuclide molecular imaging of EGFR expression would make EGFR-directed treatment more personalized and therefore more efficient. A previous study demonstrated that affibody molecule [

Indexed as

A431 xenograftaffibody moleculeepidermal growth factor receptorgallium-66PET imagingZEGFR:2377

Identifiers

PMID33672373
PMCPMC7926986
OpenAlexW3130203365

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.