Evidence map›Paper›PMID 33672352›Full record

ArticleNanomaterials (Basel, Switzerland)2021

The Effect of Selenium Nanoparticles on the Osteogenic Differentiation of MC3T3-E1 Cells.

Sang-Cheol Lee, Na-Hyun Lee, Kapil D Patel, Tae-Su Jang, Jonathan Campbell Knowles, Hae-Won Kim, Hae-Hyoung Lee, Jung-Hwan Lee

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 46 citations in OpenAlex.

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  16. Combining Porous Se@SiOInternational journal of nanomedicine · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Sang-Cheol LeeInstitute of Tissue Regeneration Engineering (ITREN), Dankook University, 119 Dandae-ro, Cheonan, Chungcheongnam-do 31116, Korea.
Na-Hyun LeeInstitute of Tissue Regeneration Engineering (ITREN), Dankook University, 119 Dandae-ro, Cheonan, Chungcheongnam-do 31116, Korea.
Kapil D PatelInstitute of Tissue Regeneration Engineering (ITREN), Dankook University, 119 Dandae-ro, Cheonan, Chungcheongnam-do 31116, Korea.
Tae-Su JangDepartment of Pre-medi, College of Medicine, Dankook University, 119 Dandae-ro, Cheonan, Chungcheongnam-do 31116, Korea.
Jonathan Campbell KnowlesInstitute of Tissue Regeneration Engineering (ITREN), Dankook University, 119 Dandae-ro, Cheonan, Chungcheongnam-do 31116, Korea.ORCID 0000-0003-3917-3446
Hae-Won KimInstitute of Tissue Regeneration Engineering (ITREN), Dankook University, 119 Dandae-ro, Cheonan, Chungcheongnam-do 31116, Korea.
Hae-Hyoung LeeInstitute of Tissue Regeneration Engineering (ITREN), Dankook University, 119 Dandae-ro, Cheonan, Chungcheongnam-do 31116, Korea.
Jung-Hwan LeeInstitute of Tissue Regeneration Engineering (ITREN), Dankook University, 119 Dandae-ro, Cheonan, Chungcheongnam-do 31116, Korea.ORCID 0000-0001-8678-5459
Dankook University · KREastman Dental Hospital · GBKorea University · KR

Funding

Global Research Development Center Program 2018K1A4A3A01064257Global Research Development Center Program 2018R1D1A1B07048020Ministry of Education 2019R1A6A1A11034536Ministry of Science and ICT, South Korea 2020R1A2C1005867National Research Foundation of Korea 2019R1C1C1002490
6 · The paper itself

Abstract

Reactive oxygen species (ROS) regulate various functions of cells, including cell death, viability, and differentiation, and nanoparticles influence ROS depending on their size and shape. Selenium is known to regulate various physiological functions, such as cell differentiations and anti-inflammatory functions, and plays an important role in the regulation of ROS as an antioxidant. This study aims to investigate the effect of selenium nanoparticles (SeNPs) on the differentiation of osteogenic MC3T3-E1 cells. After fabrication of SeNPs with a size of 25.3 ± 2.6 nm, and confirmation of its oxidase-like activity, SeNPs were added to MC3T3-E1 cells with or without H

Indexed as

MC3T3-E1nanoparticlesosteogenic differentiationreactive oxygen speciesselenium

Identifiers

PMID33672352
PMCPMC7926403
OpenAlexW3133105204

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.