Evidence map›Paper›PMID 33672316›Full record

ArticleAntioxidants (Basel, Switzerland)2021

NQO1 Deficiency Aggravates Renal Injury by Dysregulating Vps34/ATG14L Complex during Autophagy Initiation in Diabetic Nephropathy.

Geum-Lan Hong, Kyung-Hyun Kim, Chul-Ho Lee, Tae-Won Kim, Ju-Young Jung

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Geum-Lan HongDepartment of Veterinary Medicine & Institute of Veterinary Science, Chungnam National University, Daejeon 34134, Korea.ORCID 0000-0001-6680-5379
Kyung-Hyun KimDepartment of Veterinary Medicine & Institute of Veterinary Science, Chungnam National University, Daejeon 34134, Korea.
Chul-Ho LeeLaboratory Animal Resource Center Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Korea.ORCID 0000-0002-6996-5746
Tae-Won KimDepartment of Veterinary Medicine & Institute of Veterinary Science, Chungnam National University, Daejeon 34134, Korea.
Ju-Young JungDepartment of Veterinary Medicine & Institute of Veterinary Science, Chungnam National University, Daejeon 34134, Korea.ORCID 0000-0002-6355-5738
Chungnam National University · KRKorea Research Institute of Bioscience and Biotechnology · KR

Funding

This research was supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Science and ICT 2016R1A2B4008584 and 2020R1A2C1014324
6 · The paper itself

Abstract

Diabetic nephropathy (DN) is one of the causes of end-stage renal failure, featuring renal fibrosis. However, autophagy, a vital process for intracellular homeostasis, can counteract renal fibrosis. Moreover, NAD(P)H: quinone dehydrogenase 1 (NQO1) modulates the ratios of reduced/oxidized nicotinamide nucleotides, exerting a cytoprotective function. Here, to examine the role of

Indexed as

autophagydiabetic nephropathyNQO1renal injury

Identifiers

PMID33672316
PMCPMC7926338
OpenAlexW3129767014

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.