Evidence map›Paper›PMID 33672311›Full record

ArticleInternational journal of molecular sciences2021

Targeting lncRNA H19/miR-29b/COL1A1 Axis Impedes Myofibroblast Activities of Precancerous Oral Submucous Fibrosis.

Cheng-Chia Yu, Yi-Wen Liao, Pei-Ling Hsieh, Yu-Chao Chang

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
4.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 59 citations in OpenAlex.

  1. Review
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  4. Oral submucous fibrosis: pathogenesis and therapeutic approaches.International journal of oral science · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Cheng-Chia YuInstitute of Oral Sciences, Chung Shan Medical University, Taichung 40201, Taiwan.
Yi-Wen LiaoInstitute of Oral Sciences, Chung Shan Medical University, Taichung 40201, Taiwan.
Pei-Ling HsiehDepartment of Anatomy, School of Medicine, China Medical University, Taichung 404333, Taiwan.
Yu-Chao ChangDepartment of Dentistry, Chung Shan Medical University Hospital, Taichung 40201, Taiwan.ORCID 0000-0001-9731-2577
Chung Shan Medical University Hospital · TWChina Medical University · TWChung Shan Medical University · TW

Funding

Ministry of Science and Technology in Taiwan MOST 106-2314-B-040 -001 -MY3
6 · The paper itself

Abstract

Oral submucous fibrosis (OSF) is known as a potentially malignant disorder, which may result from chemical irritation due to areca nuts (such as arecoline). Emerging evidence suggests that fibrogenesis and carcinogenesis are regulated by the interaction of long noncoding RNAs (lncRNAs) and microRNAs. Among these regulators, profibrotic lncRNA

Indexed as

ArecolineBiomarkersCells, CulturedCell TransdifferentiationCollagen Type ICollagen Type I, alpha 1 ChainDown-RegulationFibroblastsGene Expression RegulationGene SilencingHumansMicroRNAsMouth MucosaMyofibroblastsOral Submucous FibrosisPrecancerous ConditionsArecolineBiomarkersCollagen Type ICollagen Type I, alpha 1 ChainH19 long non-coding RNAMicroRNAsMIRN29a microRNA, humanRNA, Long NoncodingTransforming Growth Factor betaareca nutH19miR-29boral submucous fibrosistype I collagen

Identifiers

PMID33672311
PMCPMC7926971
OpenAlexW3131621185

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.