Evidence map›Paper›PMID 33672260›Full record

ArticleInternational journal of molecular sciences2021

Divalent Cation Modulation of Ion Permeation in TMEM16 Proteins.

Dung M Nguyen, Hwoi Chan Kwon, Tsung-Yu Chen

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Chloride ions in health and disease.Bioscience reports · 2024
    Review
  4. Article
  5. Review
  6. CaInternational journal of molecular sciences · 2022
    Article
  7. Polymodal Control of TMEM16x Channels and Scramblases.International journal of molecular sciences · 2022
    Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Dung M NguyenCenter for Neuroscience, University of California, Davis, CA 95616, USA.
Hwoi Chan KwonCenter for Neuroscience, University of California, Davis, CA 95616, USA.
Tsung-Yu ChenCenter for Neuroscience, University of California, Davis, CA 95616, USA.
University of California, Davis · US

Funding

Molecular Physiology of CLC Chloride ChannelsR01GM065447 · NIGMS · UNIVERSITY OF CALIFORNIA DAVIS · PI CHEN, TSUNG-YU · 2003 to 2018
$3.9M
NIGMS NIH HHS R01 GM065447NIH HHS R01GM065447
6 · The paper itself

Abstract

Intracellular divalent cations control the molecular function of transmembrane protein 16 (TMEM16) family members. Both anion channels (such as TMEM16A) and phospholipid scramblases (such as TMEM16F) in this family are activated by intracellular Ca

Indexed as

Anoctamin-1AnoctaminsCalciumCations, DivalentCobaltElectrophysiologyHEK293 CellsHumansMagnesiumMannitolMutationPhosphatidylinositol 4,5-DiphosphatePhospholipidsPolylysineAnoctamin-1AnoctaminsCalciumCations, DivalentCobaltMagnesiumMannitolPhosphatidylinositol 4,5-DiphosphatePhospholipidsPolylysinedivalent cationspermeability ratiophospholipidsTMEM16ATMEM16F

Identifiers

PMID33672260
PMCPMC7926781
OpenAlexW3132807352

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.