ArticleMicroorganisms2021
The Autotrophic Core: An Ancient Network of 404 Reactions Converts H
Article in Microorganisms, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 31 citations in OpenAlex.
- Reduction of NAD and NMN on mineral surfaces with HCommunications chemistry · 2025Article
- Conversion of pyridoxal to pyridoxamine with NHThe FEBS journal · 2025Article
- The early evolution of the glycolytic pathway from autotrophic origins to glycogen and back.FEMS microbiology reviews · 2025Review
- Chemical Antiquity in Metabolism.Accounts of chemical research · 2024Article
- Prebiotic Synthesis of Aspartate Using Life's Metabolism as a Guide.Life (Basel, Switzerland) · 2023Article
- Article
- On the potential roles of phosphorus in the early evolution of energy metabolism.Frontiers in microbiology · 2023Review
- Serpentinization as the source of energy, electrons, organics, catalysts, nutrients and pH gradients for the origin of LUCA and life.Frontiers in microbiology · 2023Review
- The limits of metabolic heredity in protocells.Proceedings. Biological sciences · 2022Article
- A prebiotic basis for ATP as the universal energy currency.PLoS biology · 2022Article
- Uniform binding and negative catalysis at the origin of enzymes.Protein science : a publication of the Protein Society · 2022Article
- A Thermodynamic Model for Water Activity and Redox Potential in Evolution and Development.Journal of molecular evolution · 2022Article
- Energy at Origins: Favorable Thermodynamics of Biosynthetic Reactions in the Last Universal Common Ancestor (LUCA).Frontiers in microbiology · 2021Article
- Pyrophosphate and Irreversibility in Evolution, or why PPFrontiers in microbiology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
The metabolism of cells contains evidence reflecting the process by which they arose. Here, we have identified the ancient core of autotrophic metabolism encompassing 404 reactions that comprise the reaction network from H
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.