Evidence map›Paper›PMID 33672018›Full record

ArticleInternational journal of molecular sciences2021

Chimeric Virus-Like Particles of Prawn Nodavirus Displaying Hepatitis B Virus Immunodominant Region: Biophysical Properties and Cytokine Response.

Nathaniel Nyakaat Ninyio, Kok Lian Ho, Chean Yeah Yong, Hui Yee Chee, Muhajir Hamid, Hui Kian Ong, Abdul Razak Mariatulqabtiah, Wen Siang Tan

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Virus-like Particles: Fundamentals and Biomedical Applications.International journal of molecular sciences · 2022
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 2 countries.

Nathaniel Nyakaat NinyioDepartment of Microbiology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, Selangor 43400, Malaysia.ORCID 0000-0001-6819-7960
Kok Lian HoDepartment of Pathology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Selangor 43400, Malaysia.ORCID 0000-0002-5778-4729
Chean Yeah YongDepartment of Microbiology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, Selangor 43400, Malaysia.ORCID 0000-0002-0842-6386
Hui Yee CheeDepartment of Medical Microbiology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Selangor 43400, Malaysia.ORCID 0000-0002-5033-627X
Muhajir HamidDepartment of Microbiology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, Selangor 43400, Malaysia.
Hui Kian OngDepartment of Pathology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Selangor 43400, Malaysia.
Abdul Razak MariatulqabtiahDepartment of Cell and Molecular Biology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, Selangor 43400, Malaysia.ORCID 0000-0001-6999-0207
Wen Siang TanDepartment of Microbiology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, Selangor 43400, Malaysia.ORCID 0000-0001-9452-198X
Universiti Putra Malaysia · MY

Funding

Universiti Putra Malaysia GP-IPS/2018/9602500
6 · The paper itself

Abstract

Hepatitis B is a major global health challenge. In the absence of an effective treatment for the disease, hepatitis B vaccines provide protection against the viral infection. However, some individuals do not have positive immune responses after being vaccinated with the hepatitis B vaccines available in the market. Thus, it is important to develop a more protective vaccine. Previously, we showed that hepatitis B virus (HBV) 'a' determinant (aD) displayed on the prawn nodavirus capsid (Nc) and expressed in

Indexed as

AnimalsAntibodiesCapsid ProteinsCytokinesHepatitis B Surface AntigensHepatitis B VaccinesHepatitis B virusHot TemperatureImmunodominant EpitopesMiceMice, Inbred BALB CNodaviridaeSf9 CellsSignal TransductionSpodopteraVaccinationAntibodiesCapsid ProteinsCytokinesHepatitis B Surface AntigensHepatitis B VaccinesImmunodominant EpitopesVaccines, Virus-Like Particle‘a’ determinantcapsid proteincircular dichroismcytokineELISAhepatitis B virusprawn nodavirusSf9 cellsvirus-like particles

Identifiers

PMID33672018
PMCPMC7919259
OpenAlexW3131034686

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.