Evidence map›Paper›PMID 33671983›Full record

ArticleSensors (Basel, Switzerland)2021

Nano-Interstice Driven Powerless Blood Plasma Extraction in a Membrane Filter Integrated Microfluidic Device.

Jaehoon Kim, Junghyo Yoon, Jae-Yeong Byun, Hyunho Kim, Sewoon Han, Junghyun Kim, Jeong Hoon Lee, Han-Sang Jo, Seok Chung

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Sensors (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Jaehoon KimSchool of Mechanical Engineering, Korea University, Seoul 02841, Korea.
Junghyo YoonDepartment of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA 02142, USA.
Jae-Yeong ByunSchool of Mechanical Engineering, Korea University, Seoul 02841, Korea.
Hyunho KimSchool of Mechanical Engineering, Korea University, Seoul 02841, Korea.
Sewoon HanSchool of Mechanical Engineering, Korea University, Seoul 02841, Korea.
Junghyun KimSchool of Mechanical Engineering, Korea University, Seoul 02841, Korea.
Jeong Hoon LeeDepartment of Electrical Engineering, School of Electronics and Information Technology, Kwangwoon University, Seoul 01886, Korea.ORCID 0000-0001-7344-6060
Han-Sang JoAbsology, Digitalempire B-dong, 383, Simin-daero, Dongan-gu, Anyang-si, Gyeonggi-do 14057, Korea.
Seok ChungSchool of Mechanical Engineering, Korea University, Seoul 02841, Korea.
Korea University · KRKwangwoon University · KRMassachusetts Institute of Technology · US

Funding

Samsung SRFC-MA1502-51
6 · The paper itself

Abstract

Blood plasma is a source of biomarkers in blood and a simple, fast, and easy extraction method is highly required for point-of-care testing (POCT) applications. This paper proposes a membrane filter integrated microfluidic device to extract blood plasma from whole blood, without any external instrumentation. A commercially available membrane filter was integrated with a newly designed dual-cover microfluidic device to avoid leakage of the extracted plasma and remaining blood cells. Nano-interstices installed on both sides of the microfluidic channels actively draw the extracted plasma from the membrane. The developed device successfully supplied 20 μL of extracted plasma with a high extraction yield (~45%) in 16 min.

Indexed as

Lab-On-A-Chip DevicesMicrofluidic Analytical TechniquesMicrofluidicsPlasmaPoint-of-Care Testingblood plasma extractionmicrofluidicspoint-of-care testing

Identifiers

PMID33671983
PMCPMC7919272
OpenAlexW3129561734

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.