Evidence map›Paper›PMID 33671840›Full record

ArticleInternational journal of molecular sciences2021

Philippa Harding, Maria Toms, Elena Schiff, Nicholas Owen, Suzannah Bell, Ian Christopher Lloyd, Mariya Moosajee

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Abnormal function ofInternational journal of ophthalmology · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Philippa HardingInstitute of Ophthalmology, University College London, London EC1V 9EL, UK.ORCID 0000-0003-0763-3516
Maria TomsInstitute of Ophthalmology, University College London, London EC1V 9EL, UK.
Elena SchiffMoorfields Eye Hospital NHS Foundation Trust, London EC1V 2PD, UK.ORCID 0000-0002-9848-1302
Nicholas OwenInstitute of Ophthalmology, University College London, London EC1V 9EL, UK.ORCID 0000-0001-5598-6274
Suzannah BellMoorfields Eye Hospital NHS Foundation Trust, London EC1V 2PD, UK.ORCID 0000-0002-3328-3698
Ian Christopher LloydGreat Ormond Street Institute of Child Health, University College London, London WC1N 1EH, UK.ORCID 0000-0001-6460-3415
Mariya MoosajeeInstitute of Ophthalmology, University College London, London EC1V 9EL, UK.ORCID 0000-0003-1688-5360

Funding

Leadiant Biosciences /Moorfields Eye Charity /National Institute for Health Research Biomedical Research Centre at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology /Wellcome Trust 205174/Z/16/Z
6 · The paper itself

Abstract

EPHA2 is a transmembrane tyrosine kinase receptor that, when disrupted, causes congenital and age-related cataracts. Cat-Map reports 22 pathogenic

Indexed as

AdolescentAdultAlternative SplicingAnimalsCataractChildEmbryo, NonmammalianEphrin-A2FemaleHigh-Throughput Nucleotide SequencingHumansMaleMicrophthalmosMiddle AgedMorpholinosMutation, MissenseEPHA2 protein, humanEphrin-A2MorpholinosOligonucleotides, AntisenseReceptor, EphA2Zebrafish ProteinscataractscongenitaldevelopmentEPHA2eyegeneticsmicrophthalmianext-generation sequencing (NGS)whole genome sequencing (WGS)zebrafish

Identifiers

PMID33671840
PMCPMC7926380

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.