Evidence map›Paper›PMID 33671817›Full record

ArticleMolecules (Basel, Switzerland)2021

A Preliminary Study of FTIR Spectroscopy as a Potential Non-Invasive Screening Tool for Pediatric Precursor B Lymphoblastic Leukemia.

Radosław Chaber, Aneta Kowal, Paweł Jakubczyk, Christopher Arthur, Kornelia Łach, Renata Wojnarowska-Nowak, Krzysztof Kusz, Izabela Zawlik, Sylwia Paszek, Józef Cebulski

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
9.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
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  6. Infrared Spectroscopy: A New Frontier in Hematological Disease Diagnosis.International journal of molecular sciences · 2023
    Review
  7. Article
  8. Review
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  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Radosław ChaberDepartment of Pediatrics, Institute of Medical Sciences, Medical College, University of Rzeszow, Warzywna 1A, 35-310 Rzeszow, Poland.ORCID 0000-0002-6862-9142
Aneta KowalDoctoral School, Institute of Medical Sciences, Medical College, University of Rzeszow, al. T. Rejtana 16c, 35-959 Rzeszow, Poland.
Paweł JakubczykInstitute of Physics, College of Natural Sciences, University of Rzeszow, Pigonia 1, 35-310 Rzeszow, Poland.ORCID 0000-0002-5353-7915
Christopher ArthurSchool of Chemistry, University of Bristol, Cantock's Close, Bristol BS8 1TS, UK.ORCID 0000-0001-7577-8472
Kornelia ŁachDepartment of Pediatrics, Institute of Medical Sciences, Medical College, University of Rzeszow, Warzywna 1A, 35-310 Rzeszow, Poland.
Renata Wojnarowska-NowakInstitute of Physics, College of Natural Sciences, University of Rzeszow, Pigonia 1, 35-310 Rzeszow, Poland.
Krzysztof KuszInstitute of Physics, College of Natural Sciences, University of Rzeszow, Pigonia 1, 35-310 Rzeszow, Poland.
Izabela ZawlikCenter for Innovative Research in Medical and Natural Sciences, University of Rzeszow, Warzywna 1A, 35-310 Rzeszow, Poland.ORCID 0000-0001-7992-9100
Sylwia PaszekCenter for Innovative Research in Medical and Natural Sciences, University of Rzeszow, Warzywna 1A, 35-310 Rzeszow, Poland.
Józef CebulskiInstitute of Physics, College of Natural Sciences, University of Rzeszow, Pigonia 1, 35-310 Rzeszow, Poland.
University of Rzeszów · PLInstitute of Physics · PLUniversity of Bristol · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Early detection of the most common pediatric neoplasm, B-cell precursor lymphoblastic leukemia (BCP-ALL), is challenging and requires invasive bone marrow biopsies. The purpose of this study was to establish new biomarkers for early screening to detect pediatric leukemia. In this small cohort study, Fourier transform infrared (FTIR) spectra were obtained from blood sera of 10 patients with BCP-ALL and were compared with the control samples from 10 children with some conditions other than neoplasm. Using various analytical approaches, including a new physical model, some significant differences were observable. The most important include: the different peak area ratio 2965/1645 cm

Indexed as

AdolescentBone MarrowChildChild, PreschoolCohort StudiesFemaleHumansInfantMaleNeoplasm ProteinsPrecursor B-Cell Lymphoblastic Leukemia-LymphomaSpectroscopy, Fourier Transform InfraredNeoplasm Proteinsacute lymphoblastic leukemiacancer screeningLissajous curvesspectroscopy FTIR

Identifiers

PMID33671817
PMCPMC7926870
OpenAlexW3132046990

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.