Synthesis, Characterization and In Vitro Evaluation of Novel 5-Ene-thiazolo[3,2-

Serhii Holota, Sergiy Komykhov, Stepan Sysak, Andrzej Gzella, Andriy Cherkas, Roman Lesyk

Abstract read

In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

4-Thiazolidinone-Bearing Hybrid Molecules in Anticancer Drug Design.International journal of molecular sciences · 2022
Review

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Serhii HolotaDepartment of Pharmaceutical, Organic and Bioorganic Chemistry, Danylo Halytsky Lviv National Medical University, Pekarska 69, 79010 Lviv, Ukraine.ORCID 0000-0002-9892-437X

Sergiy KomykhovState Scientific Institution "Institute for Single Crystals", National Academy of Sciences of Ukraine, Nauky Ave 60, 61072 Kharkiv, Ukraine.

Stepan SysakDepartment of Pharmaceutical, Organic and Bioorganic Chemistry, Danylo Halytsky Lviv National Medical University, Pekarska 69, 79010 Lviv, Ukraine.

Andrzej GzellaDepartment of Organic Chemistry, Poznan University of Medical Sciences, Grunwaldzka 6, 60-780 Poznan, Poland.

Andriy CherkasDepartment of Internal Medicine #1, Danylo Halytsky Lviv National Medical University, Pekarska 69, 79010 Lviv, Ukraine.ORCID 0000-0002-6652-6983

Roman LesykDepartment of Pharmaceutical, Organic and Bioorganic Chemistry, Danylo Halytsky Lviv National Medical University, Pekarska 69, 79010 Lviv, Ukraine.ORCID 0000-0002-3322-0080

Funding

Ministry of Healthcare of Ukraine 0121U100690

6 · The paper itself

Abstract

The present paper is devoted to the search for drug-like molecules with anticancer properties using the thiazolo[3,2-

Indexed as

Antineoplastic AgentsCell LineCell ProliferationCrystallography, X-RayDrug Screening Assays, AntitumorHumansModels, MolecularMolecular StructureStructure-Activity RelationshipAntineoplastic Agentsanticancer activitymulticomponent reactionsSARthiazolo[3,2-b][1,2,4]triazole-6(5H)-onesZ/E-isomers

Identifiers

PMID33671733

DOI10.3390/molecules26041162

PMCPMC7926352

What OpenQuestion holds

Textmetadata

LicenceCC BY

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.