ReviewJournal of cardiovascular development and disease2021
Characterization of Degenerative Mitral Valve Disease: Differences between Fibroelastic Deficiency and Barlow's Disease.
Review in Journal of cardiovascular development and disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 56 citations in OpenAlex.
- Ultrasound Diagnosis of Marfan Syndrome Complicated by Barlow Disease With Mitral Annular Disjunction: A Case Report.Journal of clinical ultrasound : JCU · 2026Article
- Explainable machine learning and unsupervised anatomical phenotyping of mitral valve prolapse in patients with severe mitral regurgitation.BMC cardiovascular disorders · 2026Article
- The Expanding Therapeutic Armamentarium for Mitral Regurgitation: Surgical and Transcatheter Interventions.Biomedicines · 2026Review
- Prevalence and Importance of Tricuspid Valve Prolapse in Patients with Primary Mitral Regurgitation.Journal of cardiovascular development and disease · 2026Article
- Lessons learned during my 25 years as Dr. Carpentier's echocardiographer.Annals of cardiothoracic surgery · 2026Review
- Mitral Annular Disjunction: A Roadmap for the Surgeon.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2026Review
- Midterm outcomes of quadrangular versus butterfly resection in mitral valve repair for Barlow's disease.Turk gogus kalp damar cerrahisi dergisi · 2025Article
- Article
- Whole exome sequencing of 80 cases of sporadic mitral valve prolapse reveals novel disease-associated genes and variants in a Southern Chinese population.Genes & genomics · 2025Article
- [Transcatheter edge-to-edge repair using MitraClipZhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2025Article
- Characteristics of Patients With the Arrhythmogenic Mitral Valve Prolapse Syndrome and Sudden Cardiac Arrest and Sustained Ventricular Arrhythmias.Circulation. Arrhythmia and electrophysiology · 2025Article
- Translocated anterior mitral leaflet sparing is a viable treatment option for both degenerative and functional mitral valve disease.Journal of thoracic disease · 2025Article
- SimultaneousClinics (Sao Paulo, Brazil) · 2025Article
- The Burden and Trends of Degenerative Mitral Valve Disease at the Global, Regional, and National Levels From 1990 to 2021, With Projections to 2035.Global heart · 2025Article
- A prospective study on prognostic value of ventilatory efficiency in asymptomatic patients with severe primary mitral regurgitation.PloS one · 2025Article
- Arrhythmic mitral valve complex: diagnostic and therapeutic approach.Archivos de cardiologia de Mexico · 2025Review
- Molecular Mechanisms in Idiopathic Mitral Valve Chordae Tendineae Rupture: Insights from Transcriptome Analysis and Inflammation Evaluation.Journal of inflammation research · 2025Article
- Feasibility validation of automatic diagnosis of mitral valve prolapse from multi-view echocardiographic sequences based on deep neural network.European heart journal. Imaging methods and practice · 2024Article
- Characterisation of global and regional mitral annular strains in an acute porcine model.Interdisciplinary cardiovascular and thoracic surgery · 2024Article
- Quantified planar collagen distribution in healthy and degenerative mitral valve: biomechanical and clinical implications.Scientific reports · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Degenerative mitral valve disease causing mitral valve prolapse is the most common cause of primary mitral regurgitation, with two distinct phenotypes generally recognized with some major differences, i.e., fibroelastic deficiency (FED) and Barlow's disease. The aim of this review was to describe the main histological, clinical and echocardiographic features of patients with FED and Barlow's disease, highlighting the differences in diagnosis, risk stratification and patient management, but also the still significant gaps in understanding the exact pathophysiology of these two phenotypes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.