Evidence map›Paper›PMID 33671665›Full record

ReviewCancers2021

Taccalonolides: A Novel Class of Microtubule-Stabilizing Anticancer Agents.

Xiaoyan Chen, Angela Winstead, Hongtao Yu, Jiangnan Peng

Abstract readReview
In one paragraph

Review in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Allelochemical Potential ofPlants (Basel, Switzerland) · 2026
    Article
  2. Review
  3. Leveraging metabolic similarity in aScientific reports · 2026
    Article
  4. Pharmacokinetic and Biodistribution Studies of [ACS medicinal chemistry letters · 2025
    Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Virus-Induced Membrane Fusion in Neurodegenerative Disorders.Frontiers in cellular and infection microbiology · 2022
    Review
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xiaoyan ChenDepartment of Chemistry, Morgan State University, Baltimore, MD 21251, USA.
Angela WinsteadDepartment of Chemistry, Morgan State University, Baltimore, MD 21251, USA.
Hongtao YuDepartment of Chemistry, Morgan State University, Baltimore, MD 21251, USA.
Jiangnan PengDepartment of Chemistry, Morgan State University, Baltimore, MD 21251, USA.ORCID 0000-0001-5785-737X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microtubule stabilizing agents, such as paclitaxel, docetaxel, and cabazitaxel have been among the most used chemotherapeutic agents in the last decades for the treatment of a wide range of cancers in the clinic. One of the concerns that limit their use in clinical practice is their intrinsic and acquired drug resistance, which is common to most anti-cancer chemotherapeutics. Taccalonolides are a new class of microtubule stabilizers isolated from the roots of a few species in the genus of

Indexed as

anticancer agentdrug resistancemicrotubule stabilizertaccalonolide

Identifiers

PMID33671665
PMCPMC7926778

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.