ReviewSports (Basel, Switzerland)2021
Loading Recommendations for Muscle Strength, Hypertrophy, and Local Endurance: A Re-Examination of the Repetition Continuum.
Review in Sports (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 149 papers, 11 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
149 citing papers in PubMed, 11 syntheses or guidelines pooled it.
- Effect of exercise training on clinical and physiological variables in adults with myotonic dystrophy type 1: a systematic review and meta-analysis.Journal of neurology · 2026Pooled it
- Non-Specific Strength Changes Between High- and Low-Load Isotonic Resistance Training: A Systematic Review and Meta-Analysis.Sports medicine (Auckland, N.Z.) · 2026Pooled it
- Acute effects of resistance exercise on skeletal muscle glycogen depletion: A systematic review and meta-analysis.Physiological reports · 2025Pooled it
- The effects of French contrast training on lower limb athletic performance in healthy adults: a systematic review and meta-analysis.Frontiers in physiology · 2025Pooled it
- Dose-Response Modelling of Resistance Exercise Across Outcome Domains in Strength and Conditioning: A Meta-analysis.Sports medicine (Auckland, N.Z.) · 2024Pooled it
- Pooled it
- The Effects of Resistance Training on Muscular Fitness, Muscle Morphology, and Body Composition in Elite Female Athletes: A Systematic Review.Sports medicine (Auckland, N.Z.) · 2023Pooled it
- Effects of the Ketogenic Diet on Muscle Hypertrophy in Resistance-Trained Men and Women: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2022Pooled it
- Resistance training in heart failure patients: a systematic review and meta-analysis.Heart failure reviews · 2022Pooled it
- Accuracy in Predicting Repetitions to Task Failure in Resistance Exercise: A Scoping Review and Exploratory Meta-analysis.Sports medicine (Auckland, N.Z.) · 2022Pooled it
- Effects of Resistance Training Performed with Different Loads in Untrained and Trained Male Adult Individuals on Maximal Strength and Muscle Hypertrophy: A Systematic Review.International journal of environmental research and public health · 2021Pooled it
- Effects of deload periods in resistance training on muscle hypertrophy and strength endurance in untrained young men using a randomized within subject design.Scientific reports · 2026Trial
- Trial
- Casein Supplementation Timing and Exercise Performance in Soccer Players: Pre-Sleep vs. Post-Exercise Intake-A Randomized Controlled Trial.Nutrients · 2025Trial
- Partial Range, Full Gains? The Effect of 8 Weeks of Partial Range of Motion Training at Long Muscle Lengths on Elbow Flexor Hypertrophy and Strength in Trained Individuals.European journal of sport science · 2025Trial
- Evaluation of post-laryngectomy dysphagia rehabilitation using High-Resolution impedance manometry: an exploratory study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025Trial
- Arterial Stiffness and Wave Reflection Responses Following Heavy and Moderate Load Resistance Training Protocols.Journal of clinical hypertension (Greenwich, Conn.) · 2025Trial
- Biofeedback and Exercise Load Affect Accuracy of Tongue Strength Exercise Performance.Dysphagia · 2025Trial
- Long-Term Outcomes of Dysphagia Rehabilitation With an Adjustable Resistance Training Device in Laryngectomized Individuals.Head & neck · 2025Trial
- Eight weeks of resistance exercise improves mood state and intestinal permeability in healthy adults: A randomized controlled trial.Physiological reports · 2025Trial
89 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Loading recommendations for resistance training are typically prescribed along what has come to be known as the "repetition continuum", which proposes that the number of repetitions performed at a given magnitude of load will result in specific adaptations. Specifically, the theory postulates that heavy load training optimizes increases maximal strength, moderate load training optimizes increases muscle hypertrophy, and low-load training optimizes increases local muscular endurance. However, despite the widespread acceptance of this theory, current research fails to support some of its underlying presumptions. Based on the emerging evidence, we propose a new paradigm whereby muscular adaptations can be obtained, and in some cases optimized, across a wide spectrum of loading zones. The nuances and implications of this paradigm are discussed herein.
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Registered trials
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