Evidence map›Paper›PMID 33671654›Full record

ArticleInternational journal of molecular sciences2021

Permissive Modulation of Sphingosine-1-Phosphate-Enhanced Intracellular Calcium on BK

Adonis Z Wu, Tzu-Lun Ohn, Ren-Jay Shei, Huei-Fang Wu, Yong-Cyuan Chen, Hsiang-Chun Lee, Dao-Fu Dai, Sheng-Nan Wu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Editorial to the Special Issue "Electrophysiology".International journal of molecular sciences · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 3 countries.

Adonis Z WuKrannert Institute of Cardiology and Division of Cardiology, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA.ORCID 0000-0002-0059-3788
Tzu-Lun OhnInstitute of Zoology, National Taiwan University, Taipei 106319, Taiwan.ORCID 0000-0002-9636-7151
Ren-Jay SheiDivision of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine and Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham, Birmingham, AL 35294, USA.ORCID 0000-0002-7733-643X
Huei-Fang WuNeuroscience Program of Academia Sinica, Academia Sinica, Taipei 115201, Taiwan.ORCID 0000-0002-0118-3633
Yong-Cyuan ChenInstitute of Zoology, National Taiwan University, Taipei 106319, Taiwan.ORCID 0000-0002-2045-6190
Hsiang-Chun LeeDivision of Cardiology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 807378, Taiwan.ORCID 0000-0002-5877-9059
Dao-Fu DaiGraduate Institute of Clinical Medicine, Kaohsiung Medical University, Kaohsiung 807378, Taiwan.ORCID 0000-0001-7724-321X
Sheng-Nan WuDepartment of Physiology, National Cheng-Kung University Medical College, Tainan 701401, Taiwan.ORCID 0000-0002-5208-3253
National Taiwan University · TWInstitute of Molecular Biology, Academia Sinica · TWKaohsiung Medical University · TWNational Cheng Kung University · TWUniversity of Alabama at Birmingham · USUniversity of Iowa · US

Funding

The role of energy sensor signaling in mitochondrial cardiomyopathyK08HL145138 · NHLBI · UNIVERSITY OF IOWA · PI DAI, DAO-FU · 2019 to 2023
$803k
Academia Sinica AS-CFII-110-101Indiana University Health KIC2019FAKaohsiung Medical University 105KMUOR08Kaohsiung Medical University KMUH109-9R11National Science Council NSC-94-2320B-006-019National Science Council NSC 94-2627-M-002-003NHLBI NIH HHS K08 HL145138NIH HHS HL145138-02
6 · The paper itself

Abstract

Sphingosine-1-phosphate (S1P), is a signaling sphingolipid which acts as a bioactive lipid mediator. We assessed whether S1P had multiplex effects in regulating the large-conductance Ca

Indexed as

AnimalsCalciumCattleCell-Free SystemChromaffin CellsDose-Response Relationship, DrugElectrophysiologyLarge-Conductance Calcium-Activated Potassium Channel alpha SubunitsLysophospholipidsPC12 CellsRatsSphingosineCalciumKcnma1 protein, ratLarge-Conductance Calcium-Activated Potassium Channel alpha SubunitsLysophospholipidsSphingosinesphingosine 1-phosphateBKCa channelchromaffin cellintracellular Ca2+sphingosine-1-phosphate

Identifiers

PMID33671654
PMCPMC7926978
OpenAlexW3129209103

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.