Evidence map›Paper›PMID 33671624›Full record

ReviewPharmaceutics2021

Scale-up of Electrospinning: Market Overview of Products and Devices for Pharmaceutical and Biomedical Purposes.

Safaa Omer, László Forgách, Romána Zelkó, István Sebe

Abstract readReview
In one paragraph

Review in Pharmaceutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. A New Electrode Paradigm Enabled by Co-Axial Electrospinning.Small (Weinheim an der Bergstrasse, Germany) · 2026
    Article
  7. Article
  8. Article
  9. Review
  10. Small Diameter Vascular Grafts Made in Minutes.Advanced materials (Deerfield Beach, Fla.) · 2026
    Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Review
  16. Review
  17. Review
  18. Review
  19. Review
  20. Review

15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Safaa OmerUniversity Pharmacy Department of Pharmacy Administration, Semmelweis University, Hőgyes Endre Street 7-9, 1092 Budapest, Hungary.
László ForgáchDepartment of Biophysics and Radiation Biology, Semmelweis University, Tűzoltó Street 37-47, 1094 Budapest, Hungary.ORCID 0000-0001-6089-9124
Romána ZelkóUniversity Pharmacy Department of Pharmacy Administration, Semmelweis University, Hőgyes Endre Street 7-9, 1092 Budapest, Hungary.ORCID 0000-0002-5419-9137
István SebeUniversity Pharmacy Department of Pharmacy Administration, Semmelweis University, Hőgyes Endre Street 7-9, 1092 Budapest, Hungary.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recently, the electrospinning (ES) process has been extensively studied due to its potential applications in various fields, particularly pharmaceutical and biomedical purposes. The production rate using typical ES technology is usually around 0.01-1 g/h, which is lower than pharmaceutical industry production requirements. Therefore, different companies have worked to develop electrospinning equipment, technological solutions, and electrospun materials into large-scale production. Different approaches have been explored to scale-up the production mainly by increasing the nanofiber jet through multiple needles, free-surface technologies, and hybrid methods that use an additional energy source. Among them, needleless and centrifugal methods have gained the most attention and applications. Besides, the production rate reached (450 g/h in some cases) makes these methods feasible in the pharmaceutical industry. The present study overviews and compares the most recent ES approaches successfully developed for nanofibers' large-scale production and accompanying challenges with some examples of applied approaches in drug delivery systems. Besides, various types of commercial products and devices released to the markets have been mentioned.

Indexed as

electrospinning (ES)nanofibers (NFs)pharmaceutical industryscale-up

Identifiers

PMID33671624
PMCPMC7927019

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.