Evidence map›Paper›PMID 33671606›Full record

ReviewCancers2021

Isoforms of the p53 Family and Gastric Cancer: A Ménage à Trois for an Unfinished Affair.

Anais Blanchet, Agathe Bourgmayer, Jean-Emmanuel Kurtz, Georg Mellitzer, Christian Gaiddon

Erratum issuedOpen access · goldAbstract readReview
In one paragraph

Review in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 56 citations in OpenAlex.

  1. Journal of enzyme inhibition and medicinal chemistry · 2026
    Article
  2. Article
  3. The p53 Isoforms as Potential Biomarkers in Different Cancer Entities.International journal of molecular sciences · 2026
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Anais BlanchetLaboratory "Streinth" (STress REsponse and INnovative Therapies in Cancer), Inserm UMR_S 1113, IRFAC, ITI InnoVec, Université de Strasbourg, 67200 Strasbourg, France.
Agathe BourgmayerLaboratory "Streinth" (STress REsponse and INnovative Therapies in Cancer), Inserm UMR_S 1113, IRFAC, ITI InnoVec, Université de Strasbourg, 67200 Strasbourg, France.
Jean-Emmanuel KurtzLaboratory "Streinth" (STress REsponse and INnovative Therapies in Cancer), Inserm UMR_S 1113, IRFAC, ITI InnoVec, Université de Strasbourg, 67200 Strasbourg, France.
Georg MellitzerLaboratory "Streinth" (STress REsponse and INnovative Therapies in Cancer), Inserm UMR_S 1113, IRFAC, ITI InnoVec, Université de Strasbourg, 67200 Strasbourg, France.
Christian GaiddonLaboratory "Streinth" (STress REsponse and INnovative Therapies in Cancer), Inserm UMR_S 1113, IRFAC, ITI InnoVec, Université de Strasbourg, 67200 Strasbourg, France.ORCID 0000-0003-4315-3851
Inserm · FR

Funding

Alsace contre le cancer 2019/03Centre National de la Recherche Scientifique DR2ECOS Nord A2019Z2Ligue Contre le Cancer L2020A7
6 · The paper itself

Abstract

Gastric cancer is one of the most aggressive cancers, with a median survival of 12 months. This illustrates its complexity and the lack of therapeutic options, such as personalized therapy, because predictive markers do not exist. Thus, gastric cancer remains mostly treated with cytotoxic chemotherapies. In addition, less than 20% of patients respond to immunotherapy.

Indexed as

biomarkercell deathchemotherapygastric cancerimmunotherapyisoformsmetastasisp53 familypersonalized therapytumor ecosystem

Identifiers

PMID33671606
PMCPMC7926742
OpenAlexW3129822877

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.