Evidence map›Paper›PMID 33671529›Full record

ReviewNutrients2021

Common Genetic Variations Involved in the Inter-Individual Variability of Circulating Cholesterol Concentrations in Response to Diets: A Narrative Review of Recent Evidence.

Mohammad M H Abdullah, Itzel Vazquez-Vidal, David J Baer, James D House, Peter J H Jones, Charles Desmarchelier

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 25 citations in OpenAlex.

  1. Cholesterol 7 alpha-hydroxylase (Biomolecules & biomedicine · 2025
    Article
  2. Observational
  3. Article
  4. Tachol1 QTL on mouse chromosome 1 is responsible for hypercholesterolemia and diet-induced obesity.Mammalian genome : official journal of the International Mammalian Genome Society · 2024
    Article
  5. Article
  6. Biomedicines · 2024
    Review
  7. Associations of theBiomedicines · 2024
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 4 countries.

Mohammad M H AbdullahDepartment of Food Science and Nutrition, Kuwait University, Kuwait City 10002, Kuwait.ORCID 0000-0003-1804-3044
Itzel Vazquez-VidalRichardson Centre for Functional Foods & Nutraceuticals, University of Manitoba, Winnipeg, MB R3T 6C5, Canada.
David J BaerUnited States Department of Agriculture, Agricultural Research Service, Beltsville, MD 20705, USA.
James D HouseDepartment of Food and Human Nutritional Sciences, University of Manitoba, Winnipeg, MB R3T 2N2, Canada.ORCID 0000-0003-1389-5491
Peter J H JonesNutritional Fundamentals for Health, Vaudreuil-Dorion, QC J7V 5V5, Canada.
Charles DesmarchelierAix Marseille University, INRAE, INSERM, C2VN, 13005 Marseille, France.ORCID 0000-0001-9970-7089
University of Manitoba · CAAgricultural Research Service · USInserm · FRKuwait University · KW

Funding

International Life Sciences Institute 320188
6 · The paper itself

Abstract

The number of nutrigenetic studies dedicated to the identification of single nucleotide polymorphisms (SNPs) modulating blood lipid profiles in response to dietary interventions has increased considerably over the last decade. However, the robustness of the evidence-based science supporting the area remains to be evaluated. The objective of this review was to present recent findings concerning the effects of interactions between SNPs in genes involved in cholesterol metabolism and transport, and dietary intakes or interventions on circulating cholesterol concentrations, which are causally involved in cardiovascular diseases and established biomarkers of cardiovascular health. We identified recent studies (2014-2020) that reported significant SNP-diet interactions in 14 cholesterol-related genes (

Indexed as

Polymorphism, Single NucleotideCholesterolCholesterol, DietaryGene Expression RegulationHumansLipid MetabolismLipoproteinsCholesterolCholesterol, DietaryLipoproteinscardiovascular diseasesgene-diet interactiongenetic variantlipidsnutrigeneticspersonalized nutritionsingle nucleotide polymorphism

Identifiers

PMID33671529
PMCPMC7926676
OpenAlexW3135122769

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.