Evidence map›Paper›PMID 33671517›Full record

ArticleInternational journal of molecular sciences2021

Conflicting Nongenomic Effects of Progesterone in the Myometrium of Pregnant Rats.

Katsuhiko Yasuda, Aya Yoshida, Hidetaka Okada

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Katsuhiko YasudaDepartment of Obstetrics and Gynecology, Kansai Medical University, 2-5-1 Shinmachi, Hirakata, Osaka 573-1010, Japan.
Aya YoshidaDepartment of Obstetrics and Gynecology, Kansai Medical University, 2-5-1 Shinmachi, Hirakata, Osaka 573-1010, Japan.
Hidetaka OkadaDepartment of Obstetrics and Gynecology, Kansai Medical University, 2-5-1 Shinmachi, Hirakata, Osaka 573-1010, Japan.ORCID 0000-0002-7932-6999
Kansai Medical University · JP

Funding

Kansai Medical University research grant D2 (2020)
6 · The paper itself

Abstract

Recently, it has been suggested that progesterone affects the contractile activity of pregnant myometrium via nongenomic pathways; therefore, we aimed to clarify whether progesterone causes and/or inhibits pregnant myometrial contractions via nongenomic pathways. Our in vitro experiments using myometrial strips obtained from rats at 20 days of gestation revealed that progesterone caused myometrial contractions in a concentration- and time-dependent manner at concentrations up to 5 × 10

Indexed as

AnimalsCalcium Channel AgonistsCalcium Channel BlockersCalcium Channels, L-TypeFemaleHormone AntagonistsMifepristoneMyometriumNifedipineOrgan Culture TechniquesOxytocinPotassium ChloridePregnancyProgesteronePyrrolesRatsCalcium Channel AgonistsCalcium Channel BlockersCalcium Channels, L-TypeFPL 64176Hormone AntagonistsMifepristoneNifedipineOxytocinPotassium ChlorideProgesteronePyrrolesVerapamilconflicting nongenomic effectspregnant myometriumprogesteronevoltage-dependent calcium channel

Identifiers

PMID33671517
PMCPMC7926872
OpenAlexW3132064694

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.