Evidence map›Paper›PMID 33671491›Full record

ReviewNutrients2021

The Antiviral Properties of Human Milk: A Multitude of Defence Tools from Mother Nature.

Daniela Morniroli, Alessandra Consales, Beatrice Letizia Crippa, Giulia Vizzari, Federica Ceroni, Jacopo Cerasani, Lorenzo Colombo, Fabio Mosca, Maria Lorella Giannì

Abstract readReview
In one paragraph

Review in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Viruses and Human Milk: Transmission or Protection?Advances in nutrition (Bethesda, Md.) · 2023
    Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Review
  19. Article
  20. Neurological Manifestations of Perinatal Dengue.Newborn (Clarksville, Md.) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Daniela MorniroliDepartment of Clinical Sciences and Community Health, University of Milan, 20122 Milan, Italy.ORCID 0000-0003-4616-5081
Alessandra ConsalesDepartment of Clinical Sciences and Community Health, University of Milan, 20122 Milan, Italy.
Beatrice Letizia CrippaFondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Neonatal Intensive Care Unit, 20122 Milan, Italy.
Giulia VizzariDepartment of Clinical Sciences and Community Health, University of Milan, 20122 Milan, Italy.
Federica CeroniDepartment of Clinical Sciences and Community Health, University of Milan, 20122 Milan, Italy.
Jacopo CerasaniDepartment of Clinical Sciences and Community Health, University of Milan, 20122 Milan, Italy.ORCID 0000-0002-2474-0789
Lorenzo ColomboFondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Neonatal Intensive Care Unit, 20122 Milan, Italy.
Fabio MoscaDepartment of Clinical Sciences and Community Health, University of Milan, 20122 Milan, Italy.
Maria Lorella GiannìDepartment of Clinical Sciences and Community Health, University of Milan, 20122 Milan, Italy.ORCID 0000-0003-3901-9131

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The anti-infective properties of breast milk have been known for decades. In recent years, an increasing number of papers have described the variety of bioactive compounds that are present in breast milk with varying degrees of antiviral activity. However, to date, the totality of the properties of these compounds is not fully understood and, above all, their synergistic interaction is not yet known. The purpose of this review is to describe the current knowledge about the antiviral compounds in breast milk, both with specific and non-specific action against pathogens. Due to the current pandemic situation from SARS-CoV-2 (Severe acute respiratory syndrome Coronavirus-2), research has focused on a multitude of potential antiviral substances, taking breast milk as a biological model of reference. Future research is needed to expand the knowledge of these compounds, which will hopefully assist in the development of therapies applicable even at later ages.

Indexed as

Antiviral AgentsCOVID-19FemaleHumansMilk, HumanSARS-CoV-2Antiviral Agentsdocosahexaenoic acid (DHA)human milkhuman milk oligosaccharides (HMO)immunoglobulinslactoferrinlong-chain polyunsaturated fatty acids (LCPUFA)mucinsSARS-CoV-2tenascin-Cviruses

Identifiers

PMID33671491
PMCPMC7926697

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.