Evidence map›Paper›PMID 33671455›Full record

ArticleInternational journal of molecular sciences2021

Intranuclear Delivery of Nuclear Factor-Kappa B p65 in a Rat Model of Tooth Replantation.

Chung-Min Kang, Seunghan Mo, Mijeong Jeon, Ui-Won Jung, Yooseok Shin, Jin-Su Shin, Bo-Young Shin, Sang-Kyou Lee, Hyung-Jun Choi, Je Seon Song

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Deferoxamine Reduces Inflammation and Osteoclastogenesis in Avulsed Teeth.International journal of molecular sciences · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Chung-Min KangDepartment of Pediatric Dentistry, College of Dentistry, Yonsei University, Seoul 03722, Korea.ORCID 0000-0001-7813-3741
Seunghan MoDepartment of Pediatric Dentistry, College of Dentistry, Yonsei University, Seoul 03722, Korea.
Mijeong JeonDepartment of Pediatric Dentistry, College of Dentistry, Yonsei University, Seoul 03722, Korea.
Ui-Won JungDepartment of Periodontology, College of Dentistry, Yonsei University, Seoul 03722, Korea.
Yooseok ShinOral Science Research Center, College of Dentistry, Yonsei University, Seoul 03722, Korea.ORCID 0000-0003-1121-2570
Jin-Su ShinDepartment of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul 03722, Korea.
Bo-Young ShinDepartment of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul 03722, Korea.
Sang-Kyou LeeDepartment of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul 03722, Korea.
Hyung-Jun ChoiDepartment of Pediatric Dentistry, College of Dentistry, Yonsei University, Seoul 03722, Korea.
Je Seon SongDepartment of Pediatric Dentistry, College of Dentistry, Yonsei University, Seoul 03722, Korea.ORCID 0000-0001-8620-5629
Yonsei University · KR

Funding

National Research Foundation of Korea 018R1A1A1A05018328National Research Foundation of Korea 2016K1A1A2912755National Research Foundation of Korea 2017R1A2B2002537National Research Foundation of Korea 2018R1D1A1B07041657Yonsei University College of Dentistry 6-2019-0006
6 · The paper itself

Abstract

After avulsion and replantation, teeth are at risk of bone and root resorption. The present study aimed to demonstrate that the intra-nuclear transducible form of transcription modulation domain of p65 (nt-p65-TMD) can suppress osteoclast differentiation in vitro, and reduce bone resorption in a rat model of tooth replantation. Cell viability and nitric oxide release were evaluated in RAW264.7 cells using CCK-8 assay and Griess reaction kit. Osteoclast differentiation was evaluated using quantitative reverse transcriptase-polymerase chain reaction (RT-PCR) and tartrate-resistant acid phosphatase (TRAP) staining. Thirty-two maxillary rat molars were extracted and stored in saline (

Indexed as

Tooth ReplantationAnimalsCell DifferentiationCell NucleusCell SurvivalMiceModels, AnimalMolarNitric OxideOsteoclastsRatsRAW 264.7 CellsTranscription Factor RelATransduction, GeneticX-Ray MicrotomographyNitric OxideTranscription Factor RelAintra-nucleus deliverynuclear factor kappa Bosteoclasttooth replantation

Identifiers

PMID33671455
PMCPMC7922502
OpenAlexW3129426989

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.