Evidence map›Paper›PMID 33671438›Full record

ArticleBiomedicines2021

Platelet-Derived Growth Factor Stimulated Migration of Bone Marrow Mesenchymal Stem Cells into an Injectable Gelatin-Hydroxyphenyl Propionic Acid Matrix.

Wanting Niu, Teck Chuan Lim, Abdulmonem Alshihri, Ravikumar Rajappa, Lishan Wang, Motoichi Kurisawa, Myron Spector

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Wanting NiuTissue Engineering and Regenerative Medicine Laboratories, VA Boston Healthcare System, Boston, MA 02130, USA.
Teck Chuan LimTissue Engineering and Regenerative Medicine Laboratories, VA Boston Healthcare System, Boston, MA 02130, USA.
Abdulmonem AlshihriTissue Engineering and Regenerative Medicine Laboratories, VA Boston Healthcare System, Boston, MA 02130, USA.
Ravikumar RajappaTissue Engineering and Regenerative Medicine Laboratories, VA Boston Healthcare System, Boston, MA 02130, USA.ORCID 0000-0003-1177-9542
Lishan WangInstitute of Bioengineering and Nanotechnology, Singapore 138669, Singapore.
Motoichi KurisawaInstitute of Bioengineering and Nanotechnology, Singapore 138669, Singapore.
Myron SpectorTissue Engineering and Regenerative Medicine Laboratories, VA Boston Healthcare System, Boston, MA 02130, USA.
Brigham and Women's Hospital · USInstitute of Bioengineering and Nanotechnology · SGHarvard University · USVA Boston Healthcare System · US

Funding

U.S. Department of Veterans Affairs I01RX001991-01A2
6 · The paper itself

Abstract

Bone marrow mesenchymal stem cells (bMSCs) are responsible in the repair of injured tissue through differentiation into multiple cell types and secretion of paracrine factors, and thus have a broad application profile in tissue engineering/regenerative medicine, especially for the musculoskeletal system. The lesion due to injury or disease may be a closed irregular-shaped cavity deep within tissue necessitating an injectable biomaterial permissive of host (endogenous) cell migration, proliferation and differentiation. Gelatin-hydroxyphenyl propionic acid (Gtn-HPA) is a natural biopolymer hydrogel which is covalently cross-linked by horseradish peroxidase (HRP) and hydrogen peroxide (H

Indexed as

bone marrow mesenchymal stem cellsmigrationplatelet-derived growth factorproliferationstromal cell-derived factor-1α

Identifiers

PMID33671438
PMCPMC7923108
OpenAlexW3131719283

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.