Evidence map›Paper›PMID 33671425›Full record

ArticleJournal of clinical medicine2021

Skeletal Muscle Subpopulation Rearrangements upon Rhabdomyosarcoma Development through Single-Cell Mass Cytometry.

Lucia Lisa Petrilli, Federica Riccio, Giulio Giuliani, Alessandro Palma, Cesare Gargioli, Simone Vumbaca, Monika Faron, Graziana Palmieri, Luca Pasquini, Francesca Sacco and 3 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Lucia Lisa PetrilliDepartment of Biology, University of Rome "Tor Vergata", 00133 Rome, Italy.ORCID 0000-0001-6453-3031
Federica RiccioDepartment of Biology, University of Rome "Tor Vergata", 00133 Rome, Italy.ORCID 0000-0003-2939-3306
Giulio GiulianiDepartment of Biology, University of Rome "Tor Vergata", 00133 Rome, Italy.ORCID 0000-0002-4648-0076
Alessandro PalmaDepartment of Biology, University of Rome "Tor Vergata", 00133 Rome, Italy.ORCID 0000-0003-1300-5479
Cesare GargioliDepartment of Biology, University of Rome "Tor Vergata", 00133 Rome, Italy.ORCID 0000-0003-1742-3969
Simone VumbacaDepartment of Biology, University of Rome "Tor Vergata", 00133 Rome, Italy.ORCID 0000-0003-1940-3355
Monika FaronDepartment of Biology, University of Rome "Tor Vergata", 00133 Rome, Italy.
Graziana PalmieriDepartment of Biology, University of Rome "Tor Vergata", 00133 Rome, Italy.
Luca PasquiniCore Facilities, Istituto Superiore di Sanità, 00161 Rome, Italy.ORCID 0000-0002-3484-6288
Francesca SaccoDepartment of Biology, University of Rome "Tor Vergata", 00133 Rome, Italy.ORCID 0000-0001-5586-9529
Gianni CesareniDepartment of Biology, University of Rome "Tor Vergata", 00133 Rome, Italy.
Luisa CastagnoliDepartment of Biology, University of Rome "Tor Vergata", 00133 Rome, Italy.ORCID 0000-0001-5283-8671
Claudia FuocoDepartment of Biology, University of Rome "Tor Vergata", 00133 Rome, Italy.ORCID 0000-0001-8372-305X
University of Rome Tor Vergata · ITIstituto Superiore di Sanità · IT

Funding

Associazione Italiana per la Ricerca sul Cancro AIRC_IG 2013
6 · The paper itself

Abstract

The embryonal rhabdomyosarcoma (eRMS) is a soft tissue sarcoma commonly affecting the head and neck, the extremities and the genitourinary tract. To contribute to revealing the cell types that may originate this tumor, we exploited mass cytometry, a single-cell technique that, by using heavy-metal-tagged antibodies, allows the accurate monitoring of the changes occurring in the mononuclear cell composition of skeletal muscle tissue during tumor development. To this end, we compared cell populations of healthy muscles with those from spatiotemporal-induced eRMS tumors in a mouse model (LSL-Kras

Indexed as

CyTOFembryonal rhabdomyosarcomamass cytometrymesenchymal cellsmuscle populationssingle cellskeletal musclestem cellstumor heterogeneity

Identifiers

PMID33671425
PMCPMC7922544
OpenAlexW3129932404

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.