Evidence map›Paper›PMID 33671278›Full record

ReviewBiomedicines2021

Antiviral Effects of Polyphenols from Marine Algae.

Natalya N Besednova, Boris G Andryukov, Tatyana S Zaporozhets, Sergey P Kryzhanovsky, Ludmila N Fedyanina, Tatyana A Kuznetsova, Tatyana N Zvyagintseva, Mikhail Yu Shchelkanov

Open access · goldAbstract readReview
In one paragraph

Review in Biomedicines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
14.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 78 citations in OpenAlex.

  1. Review
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  11. Article
  12. From Ocean to Medicine: Harnessing Seaweed's Potential for Drug Development.International journal of molecular sciences · 2024
    Review
  13. Article
  14. Phenolic Compounds inMolecules (Basel, Switzerland) · 2023
    Review
  15. Article
  16. Review
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  19. Article
  20. Characterization ofInternational journal of environmental research and public health · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Natalya N BesednovaG.P. Somov Institute of Epidemiology and Microbiology, Russian Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, 690087 Vladivostok, Russia.
Boris G AndryukovG.P. Somov Institute of Epidemiology and Microbiology, Russian Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, 690087 Vladivostok, Russia.ORCID 0000-0003-4456-808X
Tatyana S ZaporozhetsG.P. Somov Institute of Epidemiology and Microbiology, Russian Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, 690087 Vladivostok, Russia.
Sergey P KryzhanovskyMedical Association of the Far Eastern Branch of the Russian Academy of Sciences, 690022 Vladivostok, Russia.
Ludmila N FedyaninaSchool of Biomedicine, Far Eastern Federal University (FEFU), 690091 Vladivostok, Russia.
Tatyana A KuznetsovaG.P. Somov Institute of Epidemiology and Microbiology, Russian Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, 690087 Vladivostok, Russia.
Tatyana N ZvyagintsevaElyakov Pacific Institute of Bioorganic Chemistry, FEB RAS, 690022 Vladivostok, Russia.
Mikhail Yu ShchelkanovG.P. Somov Institute of Epidemiology and Microbiology, Russian Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, 690087 Vladivostok, Russia.
Far Eastern Federal University · RUFederal Service for Surveillance on Consumer Rights Protection and Human Wellbeing · RUFar Eastern Branch of the Russian Academy of Sciences · RUPacific Institute of Bioorganic Chemistry. GB Elyakova Far Eastern Branch of the Russian Academy of Sciences · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The disease-preventive and medicinal properties of plant polyphenolic compounds have long been known. As active ingredients, they are used to prevent and treat many noncommunicable diseases. In recent decades, marine macroalgae have attracted the attention of biotechnologists and pharmacologists as a promising and almost inexhaustible source of polyphenols. This heterogeneous group of compounds contains many biopolymers with unique structure and biological properties that exhibit high anti-infective activity. In the present review, the authors focus on the antiviral potential of polyphenolic compounds (phlorotannins) from marine algae and consider the mechanisms of their action as well as other biological properties of these compounds that have effects on the progress and outcome of viral infections. Effective nutraceuticals, to be potentially developed on the basis of algal polyphenols, can also be used in the complex therapy of viral diseases. It is necessary to extend in vivo studies on laboratory animals, which subsequently will allow proceeding to clinical tests. Polyphenolic compounds have a great potential as active ingredients to be used for the creation of new antiviral pharmaceutical substances.

Indexed as

antioxidantsanti-viral activityflavonoidsmarine algaemechanism of actionpolyphenols

Identifiers

PMID33671278
PMCPMC7921925
OpenAlexW3129295737

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.