Evidence map›Paper›PMID 33671209›Full record

ReviewNanomaterials (Basel, Switzerland)2021

Chaperonins: Nanocarriers with Biotechnological Applications.

Sergio Pipaón, Marcos Gragera, M Teresa Bueno-Carrasco, Juan García-Bernalt Diego, Miguel Cantero, Jorge Cuéllar, María Rosario Fernández-Fernández, José María Valpuesta

Abstract readReview
In one paragraph

Review in Nanomaterials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Microbial Mineralization withEnvironmental science & technology · 2024
    Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sergio PipaónCentro Nacional de Biotecnología (CNB-CSIC). Darwin, 3. 28049 Madrid, Spain.ORCID 0000-0002-7702-4110
Marcos GrageraCentro Nacional de Biotecnología (CNB-CSIC). Darwin, 3. 28049 Madrid, Spain.ORCID 0000-0002-3097-1743
M Teresa Bueno-CarrascoCentro Nacional de Biotecnología (CNB-CSIC). Darwin, 3. 28049 Madrid, Spain.
Juan García-Bernalt DiegoCentro Nacional de Biotecnología (CNB-CSIC). Darwin, 3. 28049 Madrid, Spain.ORCID 0000-0001-6947-6806
Miguel CanteroCentro Nacional de Biotecnología (CNB-CSIC). Darwin, 3. 28049 Madrid, Spain.
Jorge CuéllarCentro Nacional de Biotecnología (CNB-CSIC). Darwin, 3. 28049 Madrid, Spain.ORCID 0000-0002-7789-807X
María Rosario Fernández-FernándezCentro Nacional de Biotecnología (CNB-CSIC). Darwin, 3. 28049 Madrid, Spain.ORCID 0000-0002-9128-5296
José María ValpuestaCentro Nacional de Biotecnología (CNB-CSIC). Darwin, 3. 28049 Madrid, Spain.ORCID 0000-0001-7468-8053

Funding

Comunidad de Madrid P2018/NMT-4389Ministerio de Economía, Industria y Competitividad, Gobierno de España PID2019-105872GBI00/AEI/10.13039/501100011033
6 · The paper itself

Abstract

Chaperonins are molecular chaperones found in all kingdoms of life, and as such they assist in the folding of other proteins. Structurally, chaperonins are cylinders composed of two back-to-back rings, each of which is an oligomer of ~60-kDa proteins. Chaperonins are found in two main conformations, one in which the cavity is open and ready to recognise and trap unfolded client proteins, and a "closed" form in which folding takes place. The conspicuous properties of this structure (a cylinder containing a cavity that allows confinement) and the potential to control its closure and aperture have inspired a number of nanotechnological applications that will be described in this review.

Indexed as

chaperoninsmolecular chaperonesnanocarriersnanoreactors

Identifiers

PMID33671209
PMCPMC7922521

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.