Evidence map›Paper›PMID 33671194›Full record

ArticleMetabolites2021

Novel Insights into Mice Multi-Organ Metabolism upon Exposure to a Potential Anticancer Pd(II)-Agent.

Tatiana J Carneiro, Rita Araújo, Martin Vojtek, Salomé Gonçalves-Monteiro, Carmen Diniz, Ana L M Batista de Carvalho, M Paula M Marques, Ana M Gil

Open access · goldAbstract read
In one paragraph

Article in Metabolites, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. PdJournal of medicinal chemistry · 2024
    Article
  3. Review
  4. Article
  5. Article
  6. Effect of PdInternational journal of molecular sciences · 2022
    Article
  7. Review
  8. Article
  9. PdBiomedicines · 2022
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Tatiana J CarneiroDepartment of Chemistry and CICECO-Aveiro Institute of Materials, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0003-4841-7860
Rita AraújoDepartment of Chemistry and CICECO-Aveiro Institute of Materials, University of Aveiro, 3810-193 Aveiro, Portugal.
Martin VojtekLAQV/REQUIMTE, Laboratory of Pharmacology, Department of Drug Sciences, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal.ORCID 0000-0002-9257-7020
Salomé Gonçalves-MonteiroLAQV/REQUIMTE, Laboratory of Pharmacology, Department of Drug Sciences, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal.ORCID 0000-0002-2583-5624
Carmen DinizLAQV/REQUIMTE, Laboratory of Pharmacology, Department of Drug Sciences, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal.
Ana L M Batista de CarvalhoR&D Unit "Molecular-Physical Chemistry", University of Coimbra, 3004-535 Coimbra, Portugal.ORCID 0000-0003-1280-3321
M Paula M MarquesR&D Unit "Molecular-Physical Chemistry", University of Coimbra, 3004-535 Coimbra, Portugal.ORCID 0000-0002-8391-0055
Ana M GilDepartment of Chemistry and CICECO-Aveiro Institute of Materials, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0003-3766-4364
Universidade do Porto · PTUniversity of Aveiro · PTUniversity of Coimbra · PT

Funding

COMPETE 2020, Portugal 2020 and European Community through FEDER POCI-01-0145-FEDER-0016786 and Centro-01-0145-FEDER-029956Fundação para a Ciência e a Tecnologia LAQV/REQUIMTE FCT UID/QUI/50006/2019Fundação para a Ciência e a Tecnologia PD/BD/135460/201Fundação para a Ciência e a Tecnologia Portuguese National NMR Network (PTNMR)Fundação para a Ciência e a Tecnologia SFRH/BD/145920/2019Fundação para a Ciência e a Tecnologia UIDB/00070/2020Fundação para a Ciência e a Tecnologia UIDB/50011/2020 & UIDP/50011/2020
6 · The paper itself

Abstract

Pd(II)-compounds are presently regarded as promising anticancer drugs, as an alternative to Pt(II)-based drugs (e.g., cisplatin), which typically trigger severe side-effects and acquired resistance. Dinuclear Pd(II) complexes with biogenic polyamines such as spermine (Pd

Indexed as

cisplatinmiceNMR metabolomicspalladium(II)-drugsPd2Spmtissue extracts

Identifiers

PMID33671194
PMCPMC7922283
OpenAlexW3130947638

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.