Evidence map›Paper›PMID 33671079›Full record

ReviewViruses2021

Adenovirus Core Proteins: Structure and Function.

Shermila Kulanayake, Suresh K Tikoo

Abstract readReview
In one paragraph

Review in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Adenoviral Inciting Antigen and Somatic Hypermutation in VITT.The New England journal of medicine · 2026
    Observational
  7. Review
  8. Article
  9. Genes & diseases · 2026
    Review
  10. Article
  11. Virotherapy as Gene Deliver for Anti-Cancer Therapy: A Review Article.Asian Pacific journal of cancer prevention : APJCP · 2025
    Review
  12. Article
  13. Review
  14. Mysteries of adenovirus packaging.Journal of virology · 2025
    Review
  15. Review
  16. Review
  17. Article
  18. Review
  19. Flavonoid compound fromFrontiers in cellular and infection microbiology · 2025
    Article
  20. Research progress on human adenovirus sepsis.Frontiers in pediatrics · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Shermila KulanayakeVaccine and Infectious Disease Organization-International Vaccine Center (VIDO-InterVac). University of Saskatchewan, Saskatoon, SK S7N5E3, Canada.
Suresh K TikooVaccine and Infectious Disease Organization-International Vaccine Center (VIDO-InterVac). University of Saskatchewan, Saskatoon, SK S7N5E3, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adenoviruses have served as a model for investigating viral-cell interactions and discovering different cellular processes, such as RNA splicing and DNA replication. In addition, the development and evaluation of adenoviruses as the viral vectors for vaccination and gene therapy has led to detailed investigations about adenovirus biology, including the structure and function of the adenovirus encoded proteins. While the determination of the structure and function of the viral capsid proteins in adenovirus biology has been the subject of numerous reports, the last few years have seen increased interest in elucidating the structure and function of the adenovirus core proteins. Here, we provide a review of research about the structure and function of the adenovirus core proteins in adenovirus biology.

Indexed as

AdenoviridaeAdenoviridae InfectionsAnimalsCapsid ProteinsDNA ReplicationDNA, ViralHumansViral ProteinsVirus ReplicationCapsid ProteinsDNA, ViralViral ProteinsadenovirusAdV protease cleavagecore proteinsDNA genomeDNA packagingnucleus

Identifiers

PMID33671079
PMCPMC7998265

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.