Evidence map›Paper›PMID 33671010›Full record

ArticleNanomaterials (Basel, Switzerland)2021

Screening for Effects of Inhaled Nanoparticles in Cell Culture Models for Prolonged Exposure.

Claudia Meindl, Kristin Öhlinger, Verena Zrim, Thomas Steinkogler, Eleonore Fröhlich

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Claudia MeindlCenter for Medical Research, Medical University of Graz, Stiftingtalstr. 24, 8010 Graz, Austria.
Kristin ÖhlingerCenter for Medical Research, Medical University of Graz, Stiftingtalstr. 24, 8010 Graz, Austria.
Verena ZrimCenter for Medical Research, Medical University of Graz, Stiftingtalstr. 24, 8010 Graz, Austria.
Thomas SteinkoglerInstitute of Chemical Technologies and Analytics, Vienna University of Technology, Getreidemarkt 9/164, 1060 Vienna, Austria.
Eleonore FröhlichCenter for Medical Research, Medical University of Graz, Stiftingtalstr. 24, 8010 Graz, Austria.ORCID 0000-0002-6056-6829
Medical University of Graz · ATTU Wien · AT

Funding

Österreichische Forschungsförderungsgesellschaft P 874476
6 · The paper itself

Abstract

Respiratory exposure of humans to environmental and therapeutic nanoparticles repeatedly occurs at relatively low concentrations. To identify adverse effects of particle accumulation under realistic conditions, monocultures of Calu-3 and A549 cells and co-cultures of A549 and THP-1 macrophages in the air-liquid interphase culture were exposed repeatedly to 2 µg/cm

Indexed as

air–liquid interfacecytotoxicityin vitro modelsmacrophagesnanotoxicitypolystyrene particlesproinflammatory effectsrepeated exposurerespiratory exposure

Identifiers

PMID33671010
PMCPMC7997552
OpenAlexW3134569197

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.