Evidence map›Paper›PMID 33670958›Full record

ArticleInternational journal of molecular sciences2021

Genetic Profiling of Malignant Melanoma Arising from an Ovarian Mature Cystic Teratoma: A Case Report.

Kohei Nakamura, Eriko Aimono, Reika Takamatsu, Shigeki Tanishima, Tomonari Tohyama, Katsutoshi Sasano, Hiroshi Sakuma, Hiroshi Nishihara

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Kohei NakamuraGenomics Unit, Keio Cancer Center, Keio University School of Medicine, 35 Shinanomachi, Shinjukuku, Tokyo 160-8582, Japan.
Eriko AimonoGenomics Unit, Keio Cancer Center, Keio University School of Medicine, 35 Shinanomachi, Shinjukuku, Tokyo 160-8582, Japan.
Reika TakamatsuGenomics Unit, Keio Cancer Center, Keio University School of Medicine, 35 Shinanomachi, Shinjukuku, Tokyo 160-8582, Japan.
Shigeki TanishimaDepartment of Biomedical Informatics, Kansai Division, Mitsubishi Space Software Co., Ltd., Tokyo 105-6132, Japan.
Tomonari TohyamaDepartment of Laboratory, Kumagaya General Hospital, Saitama 360-8657, Japan.
Katsutoshi SasanoDepartment of Laboratory, Kumagaya General Hospital, Saitama 360-8657, Japan.
Hiroshi SakumaDepartment of Obstetrics and Gynecology, Kumagaya General Hospital, Saitama 360-8657, Japan.
Hiroshi NishiharaGenomics Unit, Keio Cancer Center, Keio University School of Medicine, 35 Shinanomachi, Shinjukuku, Tokyo 160-8582, Japan.
Saitama Prefectural Kumagaya Girls High School · JPKeio University · JPMitsubishi Space Software (Japan) · JP

Funding

Japan Society for the Promotion of Science 20K18232
6 · The paper itself

Abstract

Ovarian mature cystic teratomas comprise tissues derived from all three germ layers. In rare cases, malignant tumors arise from ovarian mature cystic teratoma. A variety of tumors can arise from mature cystic teratoma, among which primary malignant melanoma (MM), for which no molecular analyses such as genomic sequencing have been reported to date, is exceedingly rare, thereby limiting possible therapeutic options using precision medicine. We used targeted gene sequencing to analyze the status of 160 cancer-related genes in a patient with MM arising from an ovarian mature cystic teratoma (MM-MCT).

Indexed as

Genes, NeoplasmMutationDNA Copy Number VariationsFemaleGenome, HumanHumansMelanomaMiddle AgedOvarian NeoplasmsProto-Oncogene Proteins p21(ras)PTEN PhosphohydrolaseRetinoblastoma Binding ProteinsSequence Analysis, DNATeratomaUbiquitin-Protein LigasesKRAS protein, humanProto-Oncogene Proteins p21(ras)PTEN PhosphohydrolasePTEN protein, humanRB1 protein, humanRetinoblastoma Binding ProteinsUbiquitin-Protein Ligasesgenome sequencingmalignant melanomamature cystic teratomaprecision medicine

Identifiers

PMID33670958
PMCPMC7957566
OpenAlexW3134965951

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.