Evidence map›Paper›PMID 33670941›Full record

ArticleViruses2021

Isolation of a New Infectious Pancreatic Necrosis Virus (IPNV) Variant from a Fish Farm in Scotland.

Jessica Benkaroun, Katherine Fiona Muir, Rosa Allshire, Cüneyt Tamer, Manfred Weidmann

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 3 countries.

Jessica BenkarounInstitute of Aquaculture, University of Stirling, Stirling FK9 4LA, UK.ORCID 0000-0002-5514-6256
Katherine Fiona MuirInstitute of Aquaculture, University of Stirling, Stirling FK9 4LA, UK.
Rosa AllshireInstitute of Aquaculture, University of Stirling, Stirling FK9 4LA, UK.
Cüneyt TamerDepartment of Virology, Faculty of Veterinary Medicine, Ondokuz Mayis University, 55139 Samsun, Turkey.ORCID 0000-0003-3240-8425
Manfred WeidmannInstitute of Aquaculture, University of Stirling, Stirling FK9 4LA, UK.ORCID 0000-0002-7063-7491
University of Stirling · GBOndokuz Mayıs University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aquatic virus, infectious pancreatic necrosis virus (IPNV), is known to infect various farmed fish, in particular salmonids, and is responsible for large economic losses in the aquaculture industry. Common practices to detect the virus include qPCR tests based on specific primers and serum neutralization tests for virus serotyping. Following the potential presence of IPNV viruses in a fish farm in Scotland containing vaccinated and IPNV-resistant fish, the common serotyping of the IPNV isolates was not made possible. This led us to determine the complete genome of the new IPNV isolates in order to investigate the cause of the serotyping discrepancy. Next-generation sequencing using the Illumina technology along with the sequence-independent single primer amplification (SISPA) approach was conducted to fully characterize the new Scottish isolates. With this approach, the full genome of two isolates, V1810-4 and V1810-6, was determined and analyzed. The potential origin of the virus isolates was investigated by phylogenetic analyses along with tridimensional and secondary protein structure analyses. These revealed the emergence of a new variant from one of the main virus serotypes, probably caused by the presence of selective pressure exerted by the vaccinated IPNV-resistant farmed fish.

Indexed as

AnimalsAquacultureBirnaviridae InfectionsCells, CulturedFish DiseasesFisheriesGenomeInfectious pancreatic necrosis virusOncorhynchus mykissPhylogenyScotlandSerogroupViral Structural ProteinsViral Structural Proteinsaquacultureevolutioninfectious pancreatic necrosis virusIPNVphylogenyvariant

Identifiers

PMID33670941
PMCPMC7997178
OpenAlexW3134518813

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.