Evidence map›Paper›PMID 33670877›Full record

ArticleGenes2021

DNN-m6A: A Cross-Species Method for Identifying RNA N6-Methyladenosine Sites Based on Deep Neural Network with Multi-Information Fusion.

Lu Zhang, Xinyi Qin, Min Liu, Ziwei Xu, Guangzhong Liu

Open access · goldAbstract read
In one paragraph

Article in Genes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
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  9. Review
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  11. Article
  12. M6A-BiNP: predicting NRNA biology · 2021
    Article
  13. AI applications in functional genomics.Computational and structural biotechnology journal · 2021
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Lu ZhangCollege of Information Engineering, Shanghai Maritime University, Shanghai 201306, China.
Xinyi QinCollege of Information Engineering, Shanghai Maritime University, Shanghai 201306, China.
Min LiuCollege of Information Engineering, Shanghai Maritime University, Shanghai 201306, China.
Ziwei XuPolytech Nantes, Bâtiment Ireste, 44300 Nantes, France.
Guangzhong LiuCollege of Information Engineering, Shanghai Maritime University, Shanghai 201306, China.
Shanghai Maritime University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As a prevalent existing post-transcriptional modification of RNA, N6-methyladenosine (m6A) plays a crucial role in various biological processes. To better radically reveal its regulatory mechanism and provide new insights for drug design, the accurate identification of m6A sites in genome-wide is vital. As the traditional experimental methods are time-consuming and cost-prohibitive, it is necessary to design a more efficient computational method to detect the m6A sites. In this study, we propose a novel cross-species computational method DNN-m6A based on the deep neural network (DNN) to identify m6A sites in multiple tissues of human, mouse and rat. Firstly, binary encoding (BE), tri-nucleotide composition (TNC), enhanced nucleic acid composition (ENAC),

Indexed as

Neural Networks, ComputerSequence Analysis, RNAAdenosineAnimalsHumansMiceRNAAdenosineN-methyladenosineRNABayesian hyper-parameter optimizationdeep neural networkelastic netmulti-information fusionN6-methyladenosine sites

Identifiers

PMID33670877
PMCPMC7997228
OpenAlexW3134404628

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.