Evidence map›Paper›PMID 33670794›Full record

ArticleInternational journal of molecular sciences2021

Human Costars Family Protein ABRACL Modulates Actin Dynamics and Cell Migration and Associates with Tumorigenic Growth.

Bo-Yuan Hsiao, Chia-Hsin Chen, Ho-Yi Chi, Pei-Ru Yen, Ying-Zhen Yu, Chia-Hsin Lin, Te-Ling Pang, Wei-Chi Lin, Min-Lun Li, Yi-Chen Yeh and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Bo-Yuan HsiaoInstitute of Biochemistry and Molecular Biology, National Yang-Ming University, Taipei 11221, Taiwan.
Chia-Hsin ChenInstitute of Biochemistry and Molecular Biology, National Yang-Ming University, Taipei 11221, Taiwan.
Ho-Yi ChiInstitute of Biochemistry and Molecular Biology, National Yang-Ming University, Taipei 11221, Taiwan.
Pei-Ru YenInstitute of Biochemistry and Molecular Biology, National Yang-Ming University, Taipei 11221, Taiwan.
Ying-Zhen YuInstitute of Biochemistry and Molecular Biology, National Yang-Ming University, Taipei 11221, Taiwan.
Chia-Hsin LinFaculty of Medicine, School of Medicine, National Yang-Ming University, Taipei 11221, Taiwan.
Te-Ling PangInstitute of Biochemistry and Molecular Biology, National Yang-Ming University, Taipei 11221, Taiwan.
Wei-Chi LinInstitute of Biochemistry and Molecular Biology, National Yang-Ming University, Taipei 11221, Taiwan.
Min-Lun LiInstitute of Biochemistry and Molecular Biology, National Yang-Ming University, Taipei 11221, Taiwan.
Yi-Chen YehDepartment of Pathology and Laboratory Medicine, Taipei Veterans General Hospital, Taipei 11217, Taiwan.
Teh-Ying ChouInstitute of Biochemistry and Molecular Biology, National Yang-Ming University, Taipei 11221, Taiwan.
Mei-Yu ChenInstitute of Biochemistry and Molecular Biology, National Yang-Ming University, Taipei 11221, Taiwan.
National Yang Ming Chiao Tung University · TWNational Yang Ming Chiao Tung University · TWTaipei Veterans General Hospital · TW

Funding

the Ministry of Education, Taiwan the "Cancer Progression Research Center, National Yang-Ming University" from The Featured Areas Research Center Program within the framework of the Higher Education Sprout Projectthe Ministry of Science and Technology, Taiwan MOST104-2320-B-010-020-MY3
6 · The paper itself

Abstract

Regulation of cellular actin dynamics is pivotal in driving cell motility. During cancer development, cells migrate to invade and spread; therefore, dysregulation of actin regulators is often associated with cancer progression. Here we report the role of ABRACL, a human homolog of the

Indexed as

Cell MovementActin CytoskeletonActin Depolymerizing FactorsActinsAgedCarcinogenesisCell Line, TumorCell ProliferationCell ShapeFemaleHumansIntracellular Signaling Peptides and ProteinsMaleMiddle AgedPolymerizationProtein BindingABRACL protein, humanActin Depolymerizing FactorsActinsIntracellular Signaling Peptides and Proteinsactin regulatorcell migrationcofilincolorectal cancertumorigenesis

Identifiers

PMID33670794
PMCPMC7922284
OpenAlexW3130169222

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.