Evidence map›Paper›PMID 33670772›Full record

ArticleInternational journal of molecular sciences2021

Leber Congenital Amaurosis Due to

Samuel G Jacobson, Artur V Cideciyan, Alexander Sumaroka, Alejandro J Roman, Vivian Wu, Malgorzata Swider, Rebecca Sheplock, Arun K Krishnan, Alexandra V Garafalo

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Veterinary sciences · 2025
    Article
  3. International journal of ophthalmology · 2025
    Article
  4. Review
  5. Article
  6. Article
  7. Inherited Retinal Diseases.International journal of molecular sciences · 2022
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Samuel G JacobsonDepartment of Ophthalmology, Scheie Eye Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Artur V CideciyanDepartment of Ophthalmology, Scheie Eye Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0002-2018-0905
Alexander SumarokaDepartment of Ophthalmology, Scheie Eye Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Alejandro J RomanDepartment of Ophthalmology, Scheie Eye Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0001-7368-3007
Vivian WuDepartment of Ophthalmology, Scheie Eye Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Malgorzata SwiderDepartment of Ophthalmology, Scheie Eye Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Rebecca SheplockDepartment of Ophthalmology, Scheie Eye Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Arun K KrishnanDepartment of Ophthalmology, Scheie Eye Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0002-3888-2614
Alexandra V GarafaloDepartment of Ophthalmology, Scheie Eye Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Penn Presbyterian Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gene augmentation therapy is being planned for

Indexed as

Vision, OcularAdolescentAdultChildFluorescenceGuanylate CyclaseHumansLeber Congenital AmaurosisReceptors, Cell SurfaceRetinaRetinal Cone Photoreceptor CellsTomography, Optical CoherenceYoung AdultGuanylate Cyclaseguanylate cyclase 1Receptors, Cell Surfaceclinical trialsconeoptical coherence tomographyoutcome measuresrod

Identifiers

PMID33670772
PMCPMC7922686
OpenAlexW3131709999

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.