Evidence map›Paper›PMID 33670731›Full record

ArticleAntibiotics (Basel, Switzerland)2021

Antimicrobial Prescription Pattern in Ho Teaching Hospital, Ghana: Seasonal Determination Using a Point Prevalence Survey.

Cornelius C Dodoo, Emmanuel Orman, Thelma Alalbila, Adelaide Mensah, Jonathan Jato, Kwadwo A Mfoafo, Isaac Folitse, Araba Hutton-Nyameaye, Inemesit Okon Ben, Paapa Mensah-Kane and 5 more

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Cornelius C DodooSchool of Pharmacy, University of Health and Allied Sciences, PMB 31, Ho, Ghana.ORCID 0000-0003-4369-8245
Emmanuel OrmanSchool of Pharmacy, University of Health and Allied Sciences, PMB 31, Ho, Ghana.ORCID 0000-0002-0053-5377
Thelma AlalbilaSchool of Pharmacy, University of Health and Allied Sciences, PMB 31, Ho, Ghana.ORCID 0000-0002-3769-9367
Adelaide MensahSchool of Pharmacy, University of Health and Allied Sciences, PMB 31, Ho, Ghana.ORCID 0000-0002-4329-4411
Jonathan JatoSchool of Pharmacy, University of Health and Allied Sciences, PMB 31, Ho, Ghana.ORCID 0000-0002-5508-602X
Kwadwo A MfoafoSchool of Pharmacy, University of Health and Allied Sciences, PMB 31, Ho, Ghana.ORCID 0000-0002-8720-3892
Isaac FolitseHo Teaching Hospital, P.O. Box MA 374, Ho, Ghana.
Araba Hutton-NyameayeSchool of Pharmacy, University of Health and Allied Sciences, PMB 31, Ho, Ghana.
Inemesit Okon BenSchool of Pharmacy, University of Health and Allied Sciences, PMB 31, Ho, Ghana.
Paapa Mensah-KaneSchool of Pharmacy, University of Health and Allied Sciences, PMB 31, Ho, Ghana.
Emmanuel SarkodieDepartment of Pharmacy, Kwame Nkrumah University of Science and Technology Hospital, University Post Office, KNUST, Kumasi, Ghana.ORCID 0000-0002-1464-2472
Eneyi KpokiriDepartment of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London WC1N 1AX, UK.ORCID 0000-0003-1180-1439
Misha LadvaJoint Research Office, University College London, London WC1E 6BT, UK.
Benedict AwadziHo Teaching Hospital, P.O. Box MA 374, Ho, Ghana.
Yogini JaniDepartment of Practice and Policy, University College London School of Pharmacy, London WC1N 1AX, UK.ORCID 0000-0001-5927-5429

Funding

UK Department of Health and Social Care A07
6 · The paper itself

Abstract

A standardised Global Point Prevalence Survey (PPS) tool was used to determine the antimicrobial prescription pattern in the Ho Teaching Hospital on two separate occasions in a total of 14 wards in the hospital, including dedicated wards for paediatrics and neonates. Manually collected and anonymised data were entered, validated, analysed and reported using a web-based global PPS application. With 147 and 153 patients considered in the July 2019 and January 2020 surveys, respectively, 98 patients (66.7%) and 84 patients (54.9%) had received one or more antimicrobials. The prevalence of antimicrobial use in the adult wards was 64.3% (72/112) and 53.4% (63/118) in the first and second surveys, respectively. The prevalence in the paediatric wards was 60.0% (12/20) and 62.5% (10/16), respectively, in the two surveys, while that in the neonatal wards was 93.3% (14/15) and 57.9% (11/19), respectively. β-lactams were the most used antibiotics in both periods. Malaria was the most common diagnosis requiring the use of antimicrobials in July 2019, accounting for 19.4% of the diagnoses, whereas in January 2020, it was skin and soft-tissue conditions (28.1%). This reflects a seasonal association between malaria and rainfall patterns. Out of the antimicrobials prescribed during each of the survey periods, 95% were used for empirical treatment, and this could be attributed to a number of reasons, including logistical challenges, among others, that require further exploration in the context of local, national and international policy recommendations.

Indexed as

antimicrobial stewardshipdeveloping countriespoint prevalence survey

Identifiers

PMID33670731
PMCPMC7923162

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.