Evidence map›Paper›PMID 33670658›Full record

ArticleMaterials (Basel, Switzerland)2021

A Multi-Element-Doped Porous Bioactive Glass Coating for Implant Applications.

Christie Y K Lung, Mohamed M Abdalla, Chun Hung Chu, Iris Yin, Sofiya-Roksolana Got, Jukka P Matinlinna

Abstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Christie Y K LungFaculty of Dentistry, The University of Hong Kong, Hong Kong 999077, China.
Mohamed M AbdallaFaculty of Dentistry, The University of Hong Kong, Hong Kong 999077, China.ORCID 0000-0001-7642-3948
Chun Hung ChuFaculty of Dentistry, The University of Hong Kong, Hong Kong 999077, China.ORCID 0000-0002-8167-0430
Iris YinFaculty of Dentistry, The University of Hong Kong, Hong Kong 999077, China.
Sofiya-Roksolana GotFaculty of Dentistry, The University of Hong Kong, Hong Kong 999077, China.
Jukka P MatinlinnaFaculty of Dentistry, The University of Hong Kong, Hong Kong 999077, China.ORCID 0000-0001-7656-0678

Funding

American Academy of Implant Dentistry RG-10272019-01
6 · The paper itself

Abstract

objectivesThe objectives of the study were (1) to develop a novel multi-element-doped porous 58S bioactive glass coating for titanium implants and (2) to investigate the physiochemical, cell cytotoxic and antibacterial properties of this novel coating for titanium implants.

methodsThis study employed the sol-gel method to develop a silver-, cobalt (II) oxide- and titanium dioxide-doped 58S bioactive glass coating. The surface topography and in vitro bioactivity of the new bioactive glass-coated implants were studied using scanning electron microscopy (SEM) and energy-dispersive X-ray spectroscopy. The surface nanohardness and coating degradation were evaluated using atomic force microscopy (AFM) and inductively coupled plasma atomic emission spectroscopy (ICP-AES), respectively. The cell cytotoxicity was assessed using cell viability of osteoblast-like mouse cells. The antibacterial property was examined using colony-forming units (CFUs) of the implant coating against

resultsThe multi-element-doped porous 58S bioactive glass-coated titanium implant was synthesized. SEM showed that calcium phosphate was formed on the novel coating but not on the 58S bioactive glass coating. The mean surface nanohardness of the novel coating and the 58S coating were 124 ± 24 and 50 ± 17 MPa, respectively (

conclusionA novel multielement-doped porous bioactive glass coating for titanium implants was developed. The coating displays promising biocompatibility and antibacterial activity. CLINICAL SIGNIFICANCE: the coating can be used to improve the clinical success of dental implants for patient care if it shows success in clinical trials.

Indexed as

antibacterialbioactive glasscell cytotoxicityimplant coatingtitanium

Identifiers

PMID33670658
PMCPMC7922910

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.