Evidence map›Paper›PMID 33670628›Full record

ReviewMarine drugs2021

Microalgae n-3 PUFAs Production and Use in Food and Feed Industries.

Marine Remize, Yves Brunel, Joana L Silva, Jean-Yves Berthon, Edith Filaire

Abstract readReview
In one paragraph

Review in Marine drugs, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Effects ofInternational journal of environmental research and public health · 2022
    Trial
  3. Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Harnessing microalgae for bioproducts: innovations in synthetic biology.World journal of microbiology & biotechnology · 2025
    Review
  12. Molecules (Basel, Switzerland) · 2025
    Article
  13. Article
  14. Diatom triacylglycerol metabolism: from carbon fixation to lipid droplet degradation.Biological reviews of the Cambridge Philosophical Society · 2025
    Review
  15. Article
  16. Marine drugs · 2025
    Review
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Marine RemizeGREENSEA, 3 Promenade du Sergent Jean-Louis Navarro, 34140 MÈZE, France.ORCID 0000-0002-9161-7115
Yves BrunelGREENSEA, 3 Promenade du Sergent Jean-Louis Navarro, 34140 MÈZE, France.
Joana L SilvaALLMICROALGAE-Natural Products, Avenida 25 Abril, 2445-413 Pataias, Portugal.
Jean-Yves BerthonGREENTECH, Biopôle Clermont-Limagne, 63360 SAINT BEAUZIRE, France.
Edith FilaireGREENTECH, Biopôle Clermont-Limagne, 63360 SAINT BEAUZIRE, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

N-3 polyunsaturated fatty acids (n-3 PUFAs), and especially eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), are essential compounds for human health. They have been proven to act positively on a panel of diseases and have interesting anti-oxidative, anti-inflammatory or anti-cancer properties. For these reasons, they are receiving more and more attention in recent years, especially future food or feed development. EPA and DHA come mainly from marine sources like fish or seaweed. Unfortunately, due to global warming, these compounds are becoming scarce for humans because of overfishing and stock reduction. Although increasing in recent years, aquaculture appears insufficient to meet the increasing requirements of these healthy molecules for humans. One alternative resides in the cultivation of microalgae, the initial producers of EPA and DHA. They are also rich in biochemicals with interesting properties. After defining macro and microalgae, this review synthesizes the current knowledge on n-3 PUFAs regarding health benefits and the challenges surrounding their supply within the environmental context. Microalgae n-3 PUFA production is examined and its synthesis pathways are discussed. Finally, the use of EPA and DHA in food and feed is investigated. This work aims to define better the issues surrounding n-3 PUFA production and supply and the potential of microalgae as a sustainable source of compounds to enhance the food and feed of the future.

Indexed as

Animal FeedAnimalsAquacultureDocosahexaenoic AcidsEicosapentaenoic AcidFood IndustryHumansMicroalgaeDocosahexaenoic AcidsEicosapentaenoic AcidDHAEPAfeed industryfood industrymicroalgaen-3 PUFA

Identifiers

PMID33670628
PMCPMC7922858

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.